The purpose of the Morphology Core will be to provide state-of-the-art in situ hybridization and immunohistochemistry support to participants of the Program Project Grant. The Core laboratory will a) cut tissue sections; b) perform in situ hybridization and/or immunohistochemistry; and c) maintain a tissue bank consisting of clinical specimens and experimental models available for use by PPG participants. Maintenance of a common tissue bank will significantly enhance work in individual labs and improve collaborations between participants in this PPG application. The addition of this in situ hybridization facility will significantly enhance the ability of project leaders to analyze experimental animals models and interpret the in vitro data on antioxidants, hypertension and vascular remodeling.
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| Kim, C; Fang, F; Weyand, C M et al. (2017) The life cycle of a T cell after vaccination - where does immune ageing strike? Clin Exp Immunol 187:71-81 |
| Foss, Jason D; Kirabo, Annet; Harrison, David G (2017) Do high-salt microenvironments drive hypertensive inflammation? Am J Physiol Regul Integr Comp Physiol 312:R1-R4 |
| Loperena, Roxana; Harrison, David G (2017) Oxidative Stress and Hypertensive Diseases. Med Clin North Am 101:169-193 |
| Weyand, Cornelia M; Zeisbrich, Markus; Goronzy, Jörg J (2017) Metabolic signatures of T-cells and macrophages in rheumatoid arthritis. Curr Opin Immunol 46:112-120 |
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| Itani, Hana A; McMaster Jr, William G; Saleh, Mohamed A et al. (2016) Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans. Hypertension 68:123-32 |
| Jeong, Euy-Myoung; Chung, Jaehoon; Liu, Hong et al. (2016) Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction. J Am Heart Assoc 5: |
| Yang, Zhen; Shen, Yi; Oishi, Hisashi et al. (2016) Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis. Sci Transl Med 8:331ra38 |
| Weyand, Cornelia M; Goronzy, Jörg J (2016) Aging of the Immune System. Mechanisms and Therapeutic Targets. Ann Am Thorac Soc 13 Suppl 5:S422-S428 |
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