The Morphology Core (MC) will provide technical expertise, assistance and equipment to those grant participants who need to analyze their experiments using microscopic and morphometric techniques. Expertise and assistance will be provided by core personnel in the following areas: 1) routine light microscopy and histochemical analysis, 2) enzyme histochemistry, 3) immunohistochemistry and immunocytochemistry, 4) in situ hybridization histochemistry, 5) autoradiography, 6) photomicroscopy, 7) computer-assisted image analysis, 8) morphometry, 9) electron microscopy, and 10) confocal microscopy. In addition, the MC will facilitate the acquisition, processing and storage of experimental and control tissues; maintain standards and quality control for histochemical procedures; and assist in the development of new techniques as needed.
| Whitsett, Jeffrey A; Weaver, Timothy E (2015) Alveolar development and disease. Am J Respir Cell Mol Biol 53:1-7 |
| Conkright, Juliana J; Apsley, Karen S; Martin, Emily P et al. (2010) Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C. Am J Respir Cell Mol Biol 42:181-9 |
| Xu, Yan; Zhang, Minlu; Wang, Yanhua et al. (2010) A systems approach to mapping transcriptional networks controlling surfactant homeostasis. BMC Genomics 11:451 |
| Suzuki, Takuji; Sakagami, Takuro; Young, Lisa R et al. (2010) Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy. Am J Respir Crit Care Med 182:1292-304 |
| Hardie, William D; Hagood, James S; Dave, Vrushank et al. (2010) Signaling pathways in the epithelial origins of pulmonary fibrosis. Cell Cycle 9:2769-76 |
| Whitsett, Jeffrey A; Wert, Susan E; Weaver, Timothy E (2010) Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease. Annu Rev Med 61:105-19 |
| Wang, Mei; Bridges, James P; Na, Cheng-Lun et al. (2009) Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C. J Biol Chem 284:33377-83 |
| Hardie, William D; Glasser, Stephan W; Hagood, James S (2009) Emerging concepts in the pathogenesis of lung fibrosis. Am J Pathol 175:3-16 |
| Korfhagen, Thomas R; Le Cras, Timothy D; Davidson, Cynthia R et al. (2009) Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 41:562-72 |
| Ikegami, Machiko; Weaver, Timothy E; Grant, Shawn N et al. (2009) Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation. Am J Respir Cell Mol Biol 41:433-9 |
Showing the most recent 10 out of 91 publications
