Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL071659-03
Application #
7000182
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
2004-08-04
Project End
2007-07-31
Budget Start
2004-08-04
Budget End
2005-07-31
Support Year
3
Fiscal Year
2004
Total Cost
$344,733
Indirect Cost

  Institution

Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Swain, Steve D; Meissner, Nicole N; Siemsen, Dan W et al. (2012) Pneumocystis elicits a STAT6-dependent, strain-specific innate immune response and airway hyperresponsiveness. Am J Respir Cell Mol Biol 46:290-8
Swain, Steve D; Meissner, Nicole; Han, Soo et al. (2011) Pneumocystis infection in an immunocompetent host can promote collateral sensitization to respiratory antigens. Infect Immun 79:1905-14
Saperstein, Sara; Huyck, Heidie; Kimball, Elizabeth et al. (2009) The effects of interleukin-1beta in tumor necrosis factor-alpha-induced acute pulmonary inflammation in mice. Mediators Inflamm 2009:958658
Ehrenberg, Morton S; Friedman, Alan E; Finkelstein, Jacob N et al. (2009) The influence of protein adsorption on nanoparticle association with cultured endothelial cells. Biomaterials 30:603-10
Pryhuber, Gloria S; Huyck, Heidie L; Bhagwat, Samir et al. (2008) Parenchymal cell TNF receptors contribute to inflammatory cell recruitment and respiratory failure in Pneumocystis carinii-induced pneumonia. J Immunol 181:1409-19
Swain, Steve D; Han, Soo; Harmsen, Ann et al. (2007) Pulmonary hypertension can be a sequela of prior Pneumocystis pneumonia. Am J Pathol 171:790-9
Wang, Jing; Gigliotti, Francis; Bhagwat, Samir P et al. (2007) Pneumocystis stimulates MCP-1 production by alveolar epithelial cells through a JNK-dependent mechanism. Am J Physiol Lung Cell Mol Physiol 292:L1495-505
Bruckner, Lauren; Gigliotti, Francis; Wright, Terry et al. (2006) Pneumocystis carinii infection sensitizes lung to radiation-induced injury after syngeneic marrow transplantation: role of CD4+ T cells. Am J Physiol Lung Cell Mol Physiol 290:L1087-96
Bhagwat, Samir P; Gigliotti, Francis; Xu, Haodong et al. (2006) Contribution of T cell subsets to the pathophysiology of Pneumocystis-related immunorestitution disease. Am J Physiol Lung Cell Mol Physiol 291:L1256-66
Gigliotti, Francis; Crow, Elliott L; Bhagwat, Samir P et al. (2006) Sensitized CD8+ T cells fail to control organism burden but accelerate the onset of lung injury during Pneumocystis carinii pneumonia. Infect Immun 74:6310-6

Showing the most recent 10 out of 23 publications