Transduction of Human Stem and Progenitor Cells

Crooks, Gay Miriam

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Program Projects (P01)
• Project #: 5P01HL073104-04
• Application #: 7440879
• Study Section: Heart, Lung, and Blood Initial Review Group (HLBP)
• Budget Start: 2006-04-01
• Budget End: 2007-03-31
• Support Year: 4
• Fiscal Year: 2006
• Total Cost: $321,993

Institution

• Name: Children's Hospital of Los Angeles
• DUNS #: 052277936
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90027

Publications

Lomova, Anastasia; Clark, Danielle N; Campo-Fernandez, Beatriz et al. (2018) Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair. Stem Cells :

Ha, V L; Luong, A; Li, F et al. (2017) The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation. Leukemia 31:2503-2514

Seet, Christopher S; He, Chongbin; Bethune, Michael T et al. (2017) Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids. Nat Methods 14:521-530

Shaw, Kit L; Garabedian, Elizabeth; Mishra, Suparna et al. (2017) Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency. J Clin Invest 127:1689-1699

Larson, Sarah M; Truscott, Laurel C; Chiou, Tzu-Ting et al. (2017) Pre-clinical development of gene modification of haematopoietic stem cells with chimeric antigen receptors for cancer immunotherapy. Hum Vaccin Immunother 13:1094-1104

Chin, Chee Jia; Cooper, Aaron R; Lill, Georgia R et al. (2016) Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. Stem Cells 34:1239-50

Dou, Diana R; Calvanese, Vincenzo; Sierra, Maria I et al. (2016) Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Nat Cell Biol 18:595-606

Hoban, Megan D; Lumaquin, Dianne; Kuo, Caroline Y et al. (2016) CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ cells. Mol Ther 24:1561-9

Lowe, Emily; Truscott, Laurel C; De Oliveira, Satiro N (2016) In Vitro Generation of Human NK Cells Expressing Chimeric Antigen Receptor Through Differentiation of Gene-Modified Hematopoietic Stem Cells. Methods Mol Biol 1441:241-51

Berent-Maoz, Beata; Montecino-Rodriguez, Encarnacion; Fice, Michael et al. (2015) The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). PLoS One 10:e0125414