Abstract

The Core Unit will provide services in the generation of adenoviruses and the appropriate constructs and the subsequent generation of gene-targeted and transgenic mice. Subsequently, founder mice will be identified, bred, and maintained in a core animal facility at UCSD. The Core will also be responsible for distributing the adenoviruses and mice to each individual project.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL080101-05
Application #
8114854
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2009-12-01
Budget End
2010-11-30
Support Year
5
Fiscal Year
2010
Total Cost
$319,648
Indirect Cost

  Institution

Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Hegyi, Bence; Bossuyt, Julie; Griffiths, Leigh G et al. (2018) Complex electrophysiological remodeling in postinfarction ischemic heart failure. Proc Natl Acad Sci U S A 115:E3036-E3044
Willeford, Andrew; Suetomi, Takeshi; Nickle, Audrey et al. (2018) CaMKII?-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis. JCI Insight 3:
Wood, Brent M; Simon, Mitchell; Galice, Samuel et al. (2018) Cardiac CaMKII activation promotes rapid translocation to its extra-dyadic targets. J Mol Cell Cardiol 125:18-28
Hegyi, Bence; Bossuyt, Julie; Ginsburg, Kenneth S et al. (2018) Altered Repolarization Reserve in Failing Rabbit Ventricular Myocytes: Calcium and ?-Adrenergic Effects on Delayed- and Inward-Rectifier Potassium Currents. Circ Arrhythm Electrophysiol 11:e005852
Yan, Jiajie; Zhao, Weiwei; Thomson, Justin K et al. (2018) Stress Signaling JNK2 Crosstalk With CaMKII Underlies Enhanced Atrial Arrhythmogenesis. Circ Res 122:821-835
Bers, Donald M (2017) Stabilizing ryanodine receptor gating quiets arrhythmogenic events in human heart failure and atrial fibrillation. Heart Rhythm 14:420-421
Bovo, Elisa; Huke, Sabine; Blatter, Lothar A et al. (2017) The effect of PKA-mediated phosphorylation of ryanodine receptor on SR Ca2+ leak in ventricular myocytes. J Mol Cell Cardiol 104:9-16
Kanaporis, Giedrius; Blatter, Lothar A (2017) Alternans in atria: Mechanisms and clinical relevance. Medicina (Kaunas) 53:139-149
Yuen, Garrick K; Galice, Samuel; Bers, Donald M (2017) Subcellular localization of Na/K-ATPase isoforms in ventricular myocytes. J Mol Cell Cardiol 108:158-169
Gray, Charles B B; Suetomi, Takeshi; Xiang, Sunny et al. (2017) CaMKII? subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-?B and TNF-?. J Mol Cell Cardiol 103:48-55

Showing the most recent 10 out of 233 publications