The Administrative Core (Core A) is responsible for: (a) the financial management of the Program;(b) personnel issues;(c) the handling of manuscripts, reports, abstracts, correspondence, and reprints;(d) word processing and database management support;(e) coordinating statistical support with the Biostatistical Service of the Department of Public Health;(f) coordinating formal and informal reviews of the Program;(g) general office procedures. The Molecular Biologv-Mouse Core (Core B) provides support services including: (a) breeding and genotyping genetically-modified mice;(b) carrying out biochemical analyses (c) carrying out molecular analyses;(e) acquiring and maintaining equipment;(f) coordinating the purchase, use, and disposal of radiolabeled compounds;(g) supervising and enforcing lab safety policies;(h) dishwashing and autoclaving for the entire program. The Neuroanatomv-lmaging Core (Core C) provides support services including: (a) instruction and assistance with histological procedures;(b) assistance in preparation of tissue for light and electron microscopy;(c) characterization and specificity testing of antisera;(d) instruction and assistance with quantitative imaging;(e) coordinating the purchase, use, and disposal of chemicals used in neuroanatomical experiments;(f) maintenance of the facilities and equipment for histological procedures and image analysis. The Radiotelemetrv Core (Core D) provides support services including: (a) surgical implantation of telemetry devices, osmotic minipumps and data acquisition;(b) assess blood pressure, heart rate, locomotor activity and core body temperature;(c) examine spontaneous baroreflex activity;and (d) determine autonomic tone using power spectral analysis and pharmacological approaches;(e) provide assistance with data analyses and interpretation.

Public Health Relevance

(See Instructions):

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
1P01HL096571-01
Application #
7760724
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
2009-08-05
Project End
2014-06-30
Budget Start
2009-08-05
Budget End
2010-06-30
Support Year
1
Fiscal Year
2009
Total Cost
$162,877
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Type
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
McAlinn, Helena R; Reich, Batsheva; Contoreggi, Natalina H et al. (2018) Sex Differences in the Subcellular Distribution of Corticotropin-Releasing Factor Receptor 1 in the Rat Hippocampus following Chronic Immobilization Stress. Neuroscience 383:98-113
Ma, Qian; Yang, Jianmin; Milner, Teresa A et al. (2017) SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease. JCI Insight 2:
McEwen, Bruce S; Milner, Teresa A (2017) Understanding the broad influence of sex hormones and sex differences in the brain. J Neurosci Res 95:24-39
Cole, Daniel C; Chung, Youngcheul; Gagnidze, Khatuna et al. (2017) Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology. Proc Natl Acad Sci U S A 114:13272-13277
Marques-Lopes, Jose; Tesfaye, Ephrath; Israilov, Sigal et al. (2017) Redistribution of NMDA Receptors in Estrogen-Receptor-?-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure. Neuroendocrinology 104:239-256
Almey, Anne; Milner, Teresa A; Brake, Wayne G (2016) Estrogen receptor ? and G-protein coupled estrogen receptor 1 are localized to GABAergic neurons in the dorsal striatum. Neurosci Lett 622:118-23
Faraco, Giuseppe; Park, Laibaik; Zhou, Ping et al. (2016) Hypertension enhances A?-induced neurovascular dysfunction, promotes ?-secretase activity, and leads to amyloidogenic processing of APP. J Cereb Blood Flow Metab 36:241-52
Mazid, Sanoara; Hall, Baila S; Odell, Shannon C et al. (2016) Sex differences in subcellular distribution of delta opioid receptors in the rat hippocampus in response to acute and chronic stress. Neurobiol Stress 5:37-53
Mende, Michael; Fletcher, Emily V; Belluardo, Josephine L et al. (2016) Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron 90:1189-1202
Harward, Stephen C; Hedrick, Nathan G; Hall, Charles E et al. (2016) Autocrine BDNF-TrkB signalling within a single dendritic spine. Nature 538:99-103

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