The Administrative and Biostatistical Core A is the central hub for all administrative and communications support as well as the prime statistical and analytical resource. Led by Dr. Jan Schnitzer, the Administrative Core will create an environment that will facilitate interactions between the Leaders and Researchers in each of the Projects and the other Cores, the Internal and External Advisory Boards, and the administrative personnel of the subcontracted entities: University of California, San Diego (UCSD), University of Massachusetts, Amherst (UM), University of Southern California (USC) and The Scripps Research Institute (TSRI). Core A will be the primary administrative and fiscal interface with the NHLBI and will be responsible for scientific oversight as well as ensuring timely and complete documentation as required. Additionally, Core A will provide consultation and service to the PPG investigators in the areas of study design, data analysis, mathematical modeling, simulation, presentation, and interpretation of findings. This Core will also offer various statistical and computational tools for PPG investigators, such as power analysis and sample size estimation. It will also be intimately involved in the coordinating the clinical aspects of the PPG. Regarding interactions with the other Cores and Projects, Core A will establish monitoring and documentation protocols for use of the other service Cores by project personnel and will be the final arbiter of any conflicts arising over prioritization of service Core usage by project personnel. By monitoring both Core usage and Project progress, Core A will be poised to efficiently recommend or evaluate proposed changes in service Core procedures and/or services. Dr. Schnitzer is well suited to direct Core A having previously headed a five-year multi-institutional, multi-investigator NCI program project grant. He also served as Scientific Director for the Sidney Kimmel Cancer Center (SKCC) for nine years and has directed numerous NIH, DOD and California funded research projects. Seasoned Administrative, Informational Systems, and biostatistical personnel with whom he has successfully and effectively worked with for more than ten years will assist him on a daily basis.

Public Health Relevance

The Administrative and Statistical Core is the principal organizational component through which the Project Investigators execute their responsibilities. Core A provides administrative and fiscal oversight and management to investigators by performing: grant management; review of project and core resources; personnel management; scheduling and organization of meetings; maintenance of information technology resources; data coordination and analyses, preparation and dissemination of research findings.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
Project #
Application #
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Proteogenomics Research Institute/Sys/ Med
San Diego
United States
Zip Code
Koziol, James A; Imai, Haruhiko; Dai, Liping et al. (2018) Early detection of hepatocellular carcinoma using autoantibody profiles from a panel of tumor-associated antigens. Cancer Immunol Immunother 67:835-841
Horng, Sam; Therattil, Anthony; Moyon, Sarah et al. (2017) Astrocytic tight junctions control inflammatory CNS lesion pathogenesis. J Clin Invest 127:3136-3151
Prasad, Priyaa; Molla, Mijanur Rahaman; Cui, Wei et al. (2015) Polyamide Nanogels from Generally Recognized as Safe Components and Their Toxicity in Mouse Preimplantation Embryos. Biomacromolecules 16:3491-8