Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS028121-13
Application #
6749461
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Program Officer
Jacobs, Tom P
Project Start
1990-08-01
Project End
2006-04-30
Budget Start
2004-05-01
Budget End
2006-04-30
Support Year
13
Fiscal Year
2004
Total Cost
$1,223,288
Indirect Cost
Name
University of California San Diego
Department
Neurosciences
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Maher, Pamela (2014) Proteasome Assay in Cell Lysates. Bio Protoc 4:
Brennand, K J; Simone, A; Tran, N et al. (2012) Modeling psychiatric disorders at the cellular and network levels. Mol Psychiatry 17:1239-53
Brennand, Kristen J; Simone, Anthony; Jou, Jessica et al. (2011) Modelling schizophrenia using human induced pluripotent stem cells. Nature 473:221-5
Brennand, Kristen J; Gage, Fred H (2011) Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia. Stem Cells 29:1915-22
Maher, Pamela (2008) Proteasome inhibitors prevent oxidative stress-induced nerve cell death by a novel mechanism. Biochem Pharmacol 75:1994-2006
Maher, Pamela (2008) The flavonoid fisetin promotes nerve cell survival from trophic factor withdrawal by enhancement of proteasome activity. Arch Biochem Biophys 476:139-44
Maher, Pamela; Salgado, Karmen F; Zivin, Justin A et al. (2007) A novel approach to screening for new neuroprotective compounds for the treatment of stroke. Brain Res 1173:117-25
Shackelford, Deborah A; Yeh, Richard Y (2006) Modulation of ERK and JNK activity by transient forebrain ischemia in rats. J Neurosci Res 83:476-88
Shackelford, Deborah A (2006) DNA end joining activity is reduced in Alzheimer's disease. Neurobiol Aging 27:596-605
Lapchak, Paul A (2006) Memantine, an uncompetitive low affinity NMDA open-channel antagonist improves clinical rating scores in a multiple infarct embolic stroke model in rabbits. Brain Res 1088:141-7

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