Abstract

The cytokine core laboratory has the responsibility to assay quantitative the levels of interleukin 1, IL-6, and tumor necrosis factor for all individual projects in the center. Bioassays and ELISA assays are in use for determination of these cytokines in body fluids and culture supernatant from both humans and rats. We will be available for consultation and to help develop additional assays as needed by members of the center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS031220-03
Application #
5215400
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Gebregziabher, Mulugeta; Hoel, David (2009) Applications of the Poly-K Statistical Test to Life-Time Cancer Bioassay Studies. Hum Ecol Risk Assess 15:858-875
Hatton, Jimmi; Kryscio, Richard; Ryan, Melody et al. (2006) Systemic metabolic effects of combined insulin-like growth factor-I and growth hormone therapy in patients who have sustained acute traumatic brain injury. J Neurosurg 105:843-52
Scheff, S W; Price, D A; Hicks, R R et al. (2005) Synaptogenesis in the hippocampal CA1 field following traumatic brain injury. J Neurotrauma 22:719-32
Sullivan, Patrick G; Rabchevsky, Alexander G; Keller, Jeffery N et al. (2004) Intrinsic differences in brain and spinal cord mitochondria: Implication for therapeutic interventions. J Comp Neurol 474:524-34
Dempsey, Robert J; Raghavendra Rao, Vemuganti L (2003) Cytidinediphosphocholine treatment to decrease traumatic brain injury-induced hippocampal neuronal death, cortical contusion volume, and neurological dysfunction in rats. J Neurosurg 98:867-73
Raghavendra Rao, Vemuganti L; Bowen, Kellie K; Dhodda, Vinay K et al. (2002) Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia. J Neurochem 83:1072-86
Guo, Jun-Tao; Yu, Jin; Grass, David et al. (2002) Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis. J Neurosci 22:5900-9
Adibhatla, Rao Muralikrishna; Hatcher, James F; Sailor, Kurt et al. (2002) Polyamines and central nervous system injury: spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats. Brain Res 938:81-6
Rao, V L; Dogan, A; Bowen, K K et al. (2001) Antisense knockdown of the glial glutamate transporter GLT-1 exacerbates hippocampal neuronal damage following traumatic injury to rat brain. Eur J Neurosci 13:119-28
Rao, V L; Bowen, K K; Rao, A M et al. (2001) Up-regulation of the peripheral-type benzodiazepine receptor expression and [(3)H]PK11195 binding in gerbil hippocampus after transient forebrain ischemia. J Neurosci Res 64:493-500

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