Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
2P01NS035138-20
Application #
7142900
Study Section
Special Emphasis Panel (ZNS1-SRB-A (35))
Project Start
2006-08-01
Project End
2011-07-31
Budget Start
2006-08-01
Budget End
2007-08-31
Support Year
20
Fiscal Year
2006
Total Cost
$413,710
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215
Lutz, Gabriel; Jurak, Igor; Kim, Eui Tae et al. (2017) Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors. Viruses 9:
Pan, Dongli; Kaye, Stephen B; Hopkins, Mark et al. (2014) Common and new acyclovir resistant herpes simplex virus-1 mutants causing bilateral recurrent herpetic keratitis in an immunocompetent patient. J Infect Dis 209:345-9
Pan, Dongli; Flores, Omar; Umbach, Jennifer L et al. (2014) A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. Cell Host Microbe 15:446-56
Jurak, Igor; Hackenberg, Michael; Kim, Ju Youn et al. (2014) Expression of herpes simplex virus 1 microRNAs in cell culture models of quiescent and latent infection. J Virol 88:2337-9
Wang, Jennifer P; Bowen, Glennice N; Zhou, Shenghua et al. (2012) Role of specific innate immune responses in herpes simplex virus infection of the central nervous system. J Virol 86:2273-81
Jurak, Igor; Griffiths, Anthony; Coen, Donald M (2011) Mammalian alphaherpesvirus miRNAs. Biochim Biophys Acta 1809:641-53
Kramer, Martha F; Jurak, Igor; Pesola, Jean M et al. (2011) Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia. Virology 417:239-47
Kramer, Martha F (2011) Stem-loop RT-qPCR for miRNAs. Curr Protoc Mol Biol Chapter 15:Unit 15.10
Jurak, Igor; Kramer, Martha F; Mellor, Joseph C et al. (2010) Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2. J Virol 84:4659-72
Kushnir, Anna S; Davido, David J; Schaffer, Priscilla A (2010) Role of nuclear factor Y in stress-induced activation of the herpes simplex virus type 1 ICP0 promoter. J Virol 84:188-200

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