Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS035985-09
Application #
7586717
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
9
Fiscal Year
2008
Total Cost
$201,348
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Wallner, M; Hanchar, H J; Olsen, R W (2014) Alcohol selectivity of ?3-containing GABAA receptors: evidence for a unique extracellular alcohol/imidazobenzodiazepine Ro15-4513 binding site at the ?+?- subunit interface in ??3? GABAA receptors. Neurochem Res 39:1118-26
Cushman, Jesse D; Moore, Mellissa D; Olsen, Richard W et al. (2014) The role of the ? GABA(A) receptor in ovarian cycle-linked changes in hippocampus-dependent learning and memory. Neurochem Res 39:1140-6
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Gonzalez, Claudia; Moss, Stephen J; Olsen, Richard W (2012) Ethanol promotes clathrin adaptor-mediated endocytosis via the intracellular domain of ?-containing GABAA receptors. J Neurosci 32:17874-81
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Bissiere, Stephanie; Zelikowsky, Moriel; Ponnusamy, Ravikumar et al. (2011) Electrical synapses control hippocampal contributions to fear learning and memory. Science 331:87-91
Cushman, Jesse D; Moore, Melissa D; Jacobs, Nate S et al. (2011) Behavioral pharmacogenetic analysis on the role of the ?4 GABA(A) receptor subunit in the ethanol-mediated impairment of hippocampus-dependent contextual learning. Alcohol Clin Exp Res 35:1948-59
Meera, Pratap; Wallner, Martin; Otis, Thomas S (2011) Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors. J Neurophysiol 106:2057-64
Meera, Pratap; Olsen, Richard W; Otis, Thomas S et al. (2010) Alcohol- and alcohol antagonist-sensitive human GABAA receptors: tracking ? subunit incorporation into functional receptors. Mol Pharmacol 78:918-24

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