The Administrative Core (Core B) will coordinate communication and sharing of research resources related to the Program Project. The Administrative Core will be responsible for the following activities: 1. Monitoring the progress of all Projects. 2. Coordinating the submission of our non-competitive renewal application. 3. Organizing the 3 site visits by the External Review Committee. 4. Coordinating visits of the Principal Investigators every six months. 5. Coordinating monthly PI and lab member teleconference meetings between PI visits. 6. Maintain oversight of the overall and individual budgets and resolve budgetary issues that may arise during the funding period. 7. Facilitate the patient participation in the clinical studies and in obtaining biopsy and autopsy tissue.
Core B will provide administrative support required for all components of this Program Project. The coordination of tissue sample distribution between Projects which provide an invaluable research resource. The coordination of video conferences and reviews of the project will help ensure that the appropriate progress is made by each Project, that the research remains focused on the major objectives of the Program and that maximum efforts are maintained to move the research forward.
|Pattamatta, Amrutha; Cleary, John D; Ranum, Laura P W (2018) All in the Family: Repeats and ALS/FTD. Trends Neurosci 41:247-250|
|Sznajder, ?ukasz J; Thomas, James D; Carrell, Ellie M et al. (2018) Intron retention induced by microsatellite expansions as a disease biomarker. Proc Natl Acad Sci U S A 115:4234-4239|
|Chen, Gang; Carter, Russell E; Cleary, John D et al. (2018) Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy. Neurobiol Dis 112:35-48|
|Cleary, John Douglas; Pattamatta, Amrutha; Ranum, Laura P W (2018) Repeat-associated non-ATG (RAN) translation. J Biol Chem 293:16127-16141|
|Thomas, James D; Sznajder, ?ukasz J; Bardhi, Olgert et al. (2017) Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy. Genes Dev 31:1122-1133|
|Cleary, John Douglas; Ranum, Laura Pw (2017) New developments in RAN translation: insights from multiple diseases. Curr Opin Genet Dev 44:125-134|
|Grima, Jonathan C; Daigle, J Gavin; Arbez, Nicolas et al. (2017) Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron 94:93-107.e6|
|Nakamori, Masayuki; Hamanaka, Kohei; Thomas, James D et al. (2017) Aberrant Myokine Signaling in Congenital Myotonic Dystrophy. Cell Rep 21:1240-1252|
|Zu, Tao; Cleary, John D; Liu, Yuanjing et al. (2017) RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2. Neuron 95:1292-1305.e5|
|Moloney, Christina; Rayaprolu, Sruti; Howard, John et al. (2016) Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype. Acta Neuropathol Commun 4:122|
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