Core A Project Leader: Van Vactor, David L. Project Summary / Abstract This new program will apply cutting-edge genetic tools and integrative approaches to advance our knowledge of general and specific microRNA-mediate mechanisms regulating neural circuit and synapse function in a model organism ideally suited for analysis of the cellular and molecular basis of behavior. Core A will serve to provide the administrative structure and oversight required by a multi-PI program, and to provide the coordination of frequent communication and dissemination of reagents and information necessary for this highly collaborative program to reach all of its goals. To achieve this coordination, a web-based interaction interface and a schedule of regular meetings, plus distribution of materials, will be established and monitored by the PI and two staff members.
| Goodwin, Patricia R; Meng, Alice; Moore, Jessie et al. (2018) MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila. Cell Rep 23:3776-3786 |
| Busto, Germain U; Guven-Ozkan, Tugba; Davis, Ronald L (2017) MicroRNA function in Drosophila memory formation. Curr Opin Neurobiol 43:15-24 |
| Van Vactor, David; Sigrist, Stephan J (2017) Presynaptic morphogenesis, active zone organization and structural plasticity in Drosophila. Curr Opin Neurobiol 43:119-129 |
| Busto, Germain U; Guven-Ozkan, Tugba; Chakraborty, Molee et al. (2016) Developmental inhibition of miR-iab8-3p disrupts mushroom body neuron structure and adult learning ability. Dev Biol 419:237-249 |
| Guven-Ozkan, Tugba; Busto, Germain U; Schutte, Soleil S et al. (2016) MiR-980 Is a Memory Suppressor MicroRNA that Regulates the Autism-Susceptibility Gene A2bp1. Cell Rep 14:1698-1709 |
