This Core D is designed to disseminate and provide technical support for a number of basic research resources for the aging research community in general. This is done in a series of five basic tasks -- all of them related through the use of an intelligent electronic bulletin board system for data and software dissemination and for providing documentation for the items disseminated. The first task is to disseminate the 1982, 1984, 1989, and 1994 NLTCS linked to Medicare Part A and B service use files. This data base will contain considerable technical documentation on issues such as measurement, nonresponse, and sample weight calculations. The data base will be updated as the file is modified with additional data, or the technical results of various research activities. The second task is to disseminate information on, and the results of, several different health forecasting activities. This dissemination will include both additional results of forecasting efforts that are too detailed and extensive to put into journals and access to a selected set of health forecasting programs that will allow interactive modeling sessions. In addition, we will provide the necessary technical support for such activities. The third task involves disseminating both a version of Grade of Membership software and an intelligent bulletin board system that will guide new users through the use of the program in specific applications. Both cross sectional and longitudinal forms of the GOM model will be available. The fourth task is to develop a journal on the demography of aging to provide more rapid dissemination of research results used to fill a substantive area not currently covered by demographic or gerontological journals. The fifth task is to assemble, in a data base, a number of technical reports and tables that can be accessed through the bulletin board system. The bulletin board system will also have functions in supporting other activities such as data base transfers for the ODEN networking project described in Myers' Core. The bulletin board system will be managed by Professors Woodbury and Lowrimore, each of whom have extensive computer science backgrounds. They will monitor development in interactive software systems so that innovation in the system can be made as they emerge.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Exploratory Grants (P20)
Project #
Application #
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Duke University
United States
Zip Code
Shao, Jing; Chen, Lishan; Marrs, Brian et al. (2007) SOD2 polymorphisms: unmasking the effect of polymorphism on splicing. BMC Med Genet 8:7
Bogdanovic, N; Corder, Elizabeth; Lannfelt, L et al. (2002) APOE polymorphism and clinical duration determine regional neuropathology in Swedish APP(670, 671) mutation carriers: implications for late-onset Alzheimer's disease. J Cell Mol Med 6:199-214
Corder, E H; Woodbury, M A; Manton, K G et al. (2001) Grade-of-membership sibpair linkage analysis maps IDDM11 to chromosome 14q24.3-q31. Ann Hum Genet 65:387-94
Corder, E H; Woodbury, M A; Volkmann, I et al. (2000) Density profiles of Alzheimer disease regional brain pathology for the huddinge brain bank: pattern recognition emulates and expands upon Braak staging. Exp Gerontol 35:851-64
Forsell, Y; Basun, H; Corder, E H et al. (1998) Psychotic symptoms and apolipoprotein E genotypes in an elderly population. Biol Psychiatry 44:139-40
Forsell, Y; Corder, E H; Basun, H et al. (1997) Depression and dementia in relation to apolipoprotein E polymorphism in a population sample age 75+. Biol Psychiatry 42:898-903
Corder, E H; Lannfelt, L; Viitanen, M et al. (1996) Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition. Arch Neurol 53:418-22
Basun, H; Corder, E H; Guo, Z et al. (1996) Apolipoprotein E polymorphism and stroke in a population sample aged 75 years or more. Stroke 27:1310-5