Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory Grants (P20)
Project #
1P20CA091709-01
Application #
6466457
Study Section
Special Emphasis Panel (ZCA1)
Project Start
2001-06-06
Project End
2004-05-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2001
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Xiao, Wusheng; Goswami, Prabhat C (2015) Down-regulation of peroxisome proliferator activated receptor ? coactivator 1? induces oxidative stress and toxicity of 1-(4-Chlorophenyl)-benzo-2,5-quinone in HaCaT human keratinocytes. Toxicol In Vitro 29:1332-8
Jacobs, Kristi Muldoon; Pennington, J Daniel; Bisht, Kheem S et al. (2008) SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression. Int J Biol Sci 4:291-9
Ahmad, Iman M; Abdalla, Maher Y; Aykin-Burns, Nukhet et al. (2008) 2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free Radic Biol Med 44:826-34
Ahmad, Iman M; Aykin-Burns, Nukhet; Sim, Julia E et al. (2005) Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells. J Biol Chem 280:4254-63
Niu, Gang; Krager, Kimberly J; Graham, Michael M et al. (2005) Noninvasive radiological imaging of pulmonary gene transfer and expression using the human sodium iodide symporter. Eur J Nucl Med Mol Imaging 32:534-40
Gaut, Andrew W; Niu, Gang; Krager, Kimberly J et al. (2004) Genetically targeted radiotherapy of head and neck squamous cell carcinoma using the sodium-iodide symporter (NIS). Head Neck 26:265-71
Wen, Feng; Abdalla, Maher Y; Aloman, Costica et al. (2004) Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1. J Med Virol 72:230-40
Niu, Gang; Gaut, Andrew W; Ponto, Laura L Boles et al. (2004) Multimodality noninvasive imaging of gene transfer using the human sodium iodide symporter. J Nucl Med 45:445-9
Lin, Xiao; Zhang, Fanjie; Bradbury, C Matthew et al. (2003) 2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. Cancer Res 63:3413-7