Drs. Kelvin O. Lim and Marilyn Carroll will serve as the Co-Directors of the CISA. Dr. Lim will be the Directorof the Administrative Core. This Core will assure the smooth operation of the center. Dr. Lim is responsiblefor optimizing the translational approach to research and training, ensuring the ethical conduct of researchand ensuring that all regulatory obligations are met, coordinating the various research projects and cores,assuming the fiscal responsibilities of the grant, and coordinating the resources and environment. TheAdministrative Core includes support for an Administrative Assistant who will assist Dr. Lim in the overall andday-to-day management issues of the IAC. To facilitate the generation of monthly progress reports andtracking the progress and activity across the clinical projects and cores, we will take advantage of a clinicalresearch management software package (GRID) developed by Dr. Lim. A Steering Committee will becomprised of the Center Co-Directors and all Project and Core Directors. In order to optimize collaborationswithin the CISA and the University community, we will organize a bi-monthly collaborators meeting with allCISA investigators, students, and other interested parties. In addition to these meetings, an annual retreatwill be arranged where the progress and direction of the CISA as a whole is reviewed and discussed. AnInternal Advisory Board will be formed to provide ongoing, readily accessible review of the overall goals of theCISA, the scientific content of the individual studies, and our progress. This Board will meet formally twice ayear. An External Advisory Board will be formed to provide advice to the CISA. Members of the ExternalAdvisory Board will be comprised of individuals with national and international repute with interest andexpertise in different research aspects of preclinical and clinical neurobiological research into addiction. TheExternal Advisory Board will officially meet once a year.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Exploratory Grants (P20)
Project #
1P20DA024196-01
Application #
7389922
Study Section
Special Emphasis Panel (ZDA1-MXS-M (19))
Project Start
2007-09-15
Project End
2011-09-14
Budget Start
2007-09-15
Budget End
2008-06-30
Support Year
1
Fiscal Year
2007
Total Cost
$108,673
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Chavarria-Siles, Ivan; White, Tonya; de Leeuw, Christiaan et al. (2016) Myelination-related genes are associated with decreased white matter integrity in schizophrenia. Eur J Hum Genet 24:381-6
Radke, Anna K; Zlebnik, Natalie E; Carroll, Marilyn E (2015) Cocaine withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake. Pharmacol Biochem Behav 129:51-5
Holtz, Nathan A; Carroll, Marilyn E (2015) Cocaine self-administration punished by intravenous histamine in adolescent and adult rats. Behav Pharmacol 26:393-7
Camchong, Jazmin; Macdonald 3rd, Angus W; Mueller, Bryon A et al. (2014) Changes in resting functional connectivity during abstinence in stimulant use disorder: a preliminary comparison of relapsers and abstainers. Drug Alcohol Depend 139:145-51
Patzelt, Edward H; Kurth-Nelson, Zeb; Lim, Kelvin O et al. (2014) Excessive state switching underlies reversal learning deficits in cocaine users. Drug Alcohol Depend 134:211-217
Holtz, Nathan A; Anker, Justin J; Regier, Paul S et al. (2013) Cocaine self-administration punished by i.v. histamine in rat models of high and low drug abuse vulnerability: effects of saccharin preference, impulsivity, and sex. Physiol Behav 122:32-8
Radke, Anna K; Holtz, Nathan A; Gewirtz, Jonathan C et al. (2013) Reduced emotional signs of opiate withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake. Psychopharmacology (Berl) 227:117-26
Jones, Jessica A H; Lim, Kelvin O; Wozniak, Jeffrey R et al. (2013) Context-processing abilities in chronic cocaine users. Psychol Addict Behav 27:687-95
Wisner, Krista M; Atluri, Gowtham; Lim, Kelvin O et al. (2013) Neurometrics of intrinsic connectivity networks at rest using fMRI: retest reliability and cross-validation using a meta-level method. Neuroimage 76:236-51
Holtz, Nathan A; Carroll, Marilyn E (2013) Escalation of i.v. cocaine intake in peri-adolescent vs. adult rats selectively bred for high (HiS) vs. low (LoS) saccharin intake. Psychopharmacology (Berl) 227:243-50

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