The Administrative Core will support all administrative functions related to the program project as well as the three individual research projects and functions related to services being rendered by the Proteomics and Bioinformatics Core (Core B). Personnel and resources for administrative duties will be taken from this core. Drs. Chance and Karn will devote 0.6 calendar months to administration. Ms. Schenkel, the Program Manager, will devote 2.4 calendar months of her time to administrative duties for the Program Project. She will be the administrative contact person for all subproject personnel. She will assist in the preparation of internal progress reports and will obtain financial reports from each research unit. She will also assist in coordinating all annual meetings of the External Advisory Committee with the Pis and in the preparation of reports to the NIDA. Administrative duties will include, but not be limited to (1) monitoring the progress of each pilot project, (2) acting as a hub for communication and collaboration, (3) reporting any project changes to the NIDA, (4) coordinating the monthly meetings of the Pis for each pilot project and the Proteomics and Bioinformatics Core, (5) organizing the meetings involving the Advisory Committee for the project, (6) reporting the progress of each group to the NIDA Scientific Coordinator. Ms. Williams, the Lims System Manager, will devote 2.4 calendar months to the Administrative Core. She will promote scientific interchange and collaboration through the establishment and maintenance of a Lims system that will store all the scientific data collected and analyzed in the Proteomics and Biostatics Core. She will enhance the sharing of access to resources and research output among all group members as well as the scientific community. The Administrative Core budget for years two and three will provide funds for the External Advisory Committee meetings. The meetings will be held on the Case Western Reserve University campus. Member of the External Advisory Committee will possess expertise in each project area and will monitor the progress of each pilot project and the Proteomics and Bioinformatics Core.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Exploratory Grants (P20)
Project #
5P20DA026133-02
Application #
8053326
Study Section
Special Emphasis Panel (ZDA1)
Project Start
Project End
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
2
Fiscal Year
2010
Total Cost
$86,171
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Guyuron, Bahman; Yohannes, Elizabeth; Miller, Robert et al. (2014) Electron microscopic and proteomic comparison of terminal branches of the trigeminal nerve in patients with and without migraine headaches. Plast Reconstr Surg 134:796e-805e
Golden, Jackelyn B; McCormick, Thomas S; Ward, Nicole L (2013) IL-17 in psoriasis: implications for therapy and cardiovascular co-morbidities. Cytokine 62:195-201
Meisch, Jeffrey P; Vogel, Ryan M; Schlatzer, Daniela M et al. (2013) Human ?-defensin 3 induces STAT1 phosphorylation, tyrosine phosphatase activity, and cytokine synthesis in T cells. J Leukoc Biol 94:459-71
Schlatzer, Daniela M; Sugalski, Julia M; Chen, Yanwen et al. (2013) Plasma proteome analysis reveals overlapping, yet distinct mechanisms of immune activation in chronic HCV and HIV infections. J Acquir Immune Defic Syndr 63:563-71
Schlatzer, Daniela M; Sugalski, Julia; Dazard, Jean-Eudes et al. (2012) A quantitative proteomic approach for detecting protein profiles of activated human myeloid dendritic cells. J Immunol Methods 375:39-45
Yohannes, Elizabeth; Ghosh, Santosh K; Jiang, Bin et al. (2011) Proteomic signatures of human oral epithelial cells in HIV-infected subjects. PLoS One 6:e27816
Liu, Yu; Patel, Sanjay; Nibbe, Rod et al. (2011) Systems biology analyses of gene expression and genome wide association study data in obstructive sleep apnea. Pac Symp Biocomput :14-25
McCormick, Thomas S; Weinberg, Aaron (2010) Epithelial cell-derived antimicrobial peptides are multifunctional agents that bridge innate and adaptive immunity. Periodontol 2000 54:195-206