OVERALL The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE) is a statewide network of graduate and undergraduate universities in Kansas and Oklahoma that work cooperatively to improve biomedical research in Kansas. Kansas formed such a network in 2001 (Kansas BRIN) and has successfully continued as the Kansas INBRE. The University of Kansas Medical Center (KUMC) is the Lead Institution and works closely with 2 other Graduate Partner Institutions (GPI) (University of Kansas-Lawrence, KU-L; Kansas State University, KSU;) and 7 institutions focused on undergraduate student training [Undergraduate Partner Institution or UPI: Emporia State University (ESU), Fort Hays State University (FHSU), Haskell Indian Nations University (HINU), Langston University (LU, Langston, OK), Pittsburg State University (PSU), Washburn University (WU), and Wichita State University, WSU]. The K-INBRE is focused on 1) ethnic diversity and geographic considerations in our large but sparsely populated state, 2) the power of mentored, team science, and 3) a skilled Kansas workforce and integration with existing educational and training programs. The long-range objectives are to promote multidisciplinary research networks with a focus on Cell and Developmental Biology; increase the research base and capacity through research support; provide research opportunities for trainees; serve as a pipeline for students to continue in health research careers; and enhance science and technology knowledge of Kansas workforce. To achieve the objectives of the K-INBRE, the proposal contains key elements as 4 Specific Aims and 3 Cores.
Aim 1 seeks to improve the multidisciplinary research network in Kansas. The K-INBRE Administrative Core provides oversight of all K-INBRE functions and includes the Incentives & Awards Committee and the Undergraduate Research Office. The Communications Core focuses on network communications, scholarship and internal evaluations.
Aim 2 enhances science and technology knowledge through sophisticated bioinformatics technology and education. The K-INBRE Bioinformatics Core continues to focus on enhanced genomics bioinformatics, bioinformatics education, outreach and education.
Aim 3 stimulates basic, translational and entrepreneurial research in Kansas via mentored, interdisciplinary research opportunities. The Mentoring Core oversees 2 mentoring programs and the Developmental Research Project Program. The K-INBRE operates as a very successful program and continues to improve and expand our efforts in Cell and Developmental Biology research in Kansas. New innovations include an expansion of our pipeline to high school students and integration with existing educational/training programs in Kansas, as well as strong collaborations with other IDeA (INBRE and COBRE) programs in Kansas and in the Central IDeA Region.

Public Health Relevance

The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE) is a statewide network of Universities in Kansas and Oklahoma that work together to augment the research infrastructure, training, research productivity, and career development of biomedical researchers in Kansas. The K-INBRE has diverse programs to support researcher pipelines and research careers, build research infrastructure, and enhance the competitiveness of Kansas biomedical researchers. The strength of the program is its long-standing collaborative network, and success in pipeline development for students, trainees, and faculty in biomedical research. K- INBRE operates through four outstanding cores that have strengths in mentoring, bioinformatics, communications, and administration of this longstanding Kansas program.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103418-19
Application #
9674040
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Arora, Krishan
Project Start
2001-09-18
Project End
2024-04-30
Budget Start
2019-05-10
Budget End
2020-04-30
Support Year
19
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Kansas
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160
Kaplan, Sam V; Limbocker, Ryan A; Levant, Beth et al. (2018) Regional differences in dopamine release in the R6/2 mouse caudate putamen. Electroanalysis 30:1066-1072
Reiner, David J; Lundquist, Erik A (2018) Small GTPases. WormBook 2018:1-65
Roggenkamp, Emily; Giersch, Rachael M; Schrock, Madison N et al. (2018) Tuning CRISPR-Cas9 Gene Drives in Saccharomyces cerevisiae. G3 (Bethesda) 8:999-1018
Evans, Kara C; Benomar, Saida; Camuy-VĂ©lez, Lennel A et al. (2018) Quorum-sensing control of antibiotic resistance stabilizes cooperation in Chromobacterium violaceum. ISME J 12:1263-1272
Basgall, Erianna M; Goetting, Samantha C; Goeckel, Megan E et al. (2018) Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiae. Microbiology 164:464-474
Alam, S M K; Jasti, S; Kshirsagar, S K et al. (2018) Trophoblast Glycoprotein (TPGB/5T4) in Human Placenta: Expression, Regulation, and Presence in Extracellular Microvesicles and Exosomes. Reprod Sci 25:185-197
Raman, Archana; Parnell, Stephen C; Zhang, Yan et al. (2018) Periostin overexpression in collecting ducts accelerates renal cyst growth and fibrosis in polycystic kidney disease. Am J Physiol Renal Physiol :
Sawant, Ketki; Chen, Yujun; Kotian, Nirupama et al. (2018) Rap1 GTPase promotes coordinated collective cell migration in vivo. Mol Biol Cell 29:2656-2673
Wu, Long; Zhang, Xin; Zhao, Liqin (2018) Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention. J Neurosci 38:6665-6681
Franklin, Meghan Whitney; Slusky, Joanna S G (2018) Tight Turns of Outer Membrane Proteins: An Analysis of Sequence, Structure, and Hydrogen Bonding. J Mol Biol 430:3251-3265

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