The goal of the Developmental Research Project Program of the Maine INBRE (ME-INBRE) is to support the research and career development of exceptional INBRE-affiliated faculty who are engaged in biomedical research and research training in comparative functional genomics. Faculty will be selected on a competitive basis, via review by the ME-INBRE External Advisory Committee (EAC), from applicants who respond to Funding Opportunity Announcements (FOA) distributed within the ME-INBRE network. This program has two specific aims. The first is to provide Investigator awards for Research Projects. Selected Investigators will be expected to devote 50% effort to their project, actively engage scientific advisors and implement individualized development plans, mentor students and/or postdoctoral fellows, submit quarterly progress reports, publish in peer-reviewed journals, present at national and/or international meetings, and participate in INBRE-sponsored workshops. Investigators at research institutions will also be expected to apply for independent R01-level research funding by the end of the second year of funding. Investigator appointments will be renewed annually for up to 3 years contingent on review of progress by the ME-INBRE Principal Investigator (PI), Program Coordinator (PC), Steering Committee and EAC, with the possibility of competitive renewal for up to 2 additional years.
The second aim of the program is to provide Research Training Faculty awards for Pilot Projects at undergraduate institutions led by faculty researchers who have demonstrated an ability to effectively engage students in cutting-edge research in comparative functional genomics involving computational biology and/or bioinformatics. Research Training Faculty will devote 15-25% effort to their project, actively engage scientific advisors and implement individualized development plans, engage students in research, submit quarterly progress reports, present at regional and/or national meetings, submit the results for publication in peer-reviewed journals, and participate in INBRE-sponsored workshops. Research Training Faculty will build biomedical research capacity by providing high-level opportunities for student research and training at undergraduate partner institutions. For both aims, emphasis will be placed on mentorship (both of faculty and their students and trainees) and evaluation. Successful implementation of the two aims of the Developmental Research Projects Program will be facilitated by annual evaluations of the EAC and assessed by a final summative evaluation carried out by the PI, PC, EAC, Evaluation Coordinator, and an AAAS review panel.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103423-20
Application #
9918417
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
20
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Mount Desert Island Biological Lab
Department
Type
DUNS #
077470003
City
Salsbury Cove
State
ME
Country
United States
Zip Code
04672
DuShane, Jeanne K; Wilczek, Michael P; Mayberry, Colleen L et al. (2018) ERK Is a Critical Regulator of JC Polyomavirus Infection. J Virol 92:
Waldron, Ashley L; Schroder, Patricia A; Bourgon, Kelly L et al. (2018) Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity. J Diabetes Complications 32:249-257
Christie, Andrew E; Miller, Alexandra; Fernandez, Rebecca et al. (2018) Non-amidated and amidated members of the C-type allatostatin (AST-C) family are differentially distributed in the stomatogastric nervous system of the American lobster, Homarus americanus. Invert Neurosci 18:2
Fisher, Harrison P; Pascual, Micah G; Jimenez, Sylvia I et al. (2018) De novo assembly of a transcriptome for the cricket Gryllus bimaculatus prothoracic ganglion: An invertebrate model for investigating adult central nervous system compensatory plasticity. PLoS One 13:e0199070
Dickinson, Patsy S; Armstrong, Matthew K; Dickinson, Evyn S et al. (2018) Three members of a peptide family are differentially distributed and elicit differential state-dependent responses in a pattern generator-effector system. J Neurophysiol 119:1767-1781
Maginnis, Melissa S (2018) Virus-Receptor Interactions: The Key to Cellular Invasion. J Mol Biol 430:2590-2611
Breton, Timothy S; Nettleton, Jeremy C; O'Connell, Brennah et al. (2018) Fine-scale population genetic structure of sugar kelp, Saccharina latissima (Laminariales, Phaeophyceae), in eastern Maine, USA. Phycologia 57:32-40
Hampton, Thomas H; Jackson, Craig; Jung, Dawoon et al. (2018) Arsenic Reduces Gene Expression Response to Changing Salinity in Killifish. Environ Sci Technol 52:8811-8821
Le, Phuong M; Silvestri, Vanesa L; Redstone, Samuel C et al. (2018) Cross-linking by epichlorohydrin and diepoxybutane correlates with cytotoxicity and leads to apoptosis in human leukemia (HL-60) cells. Toxicol Appl Pharmacol 352:19-27
Bavis, Ryan W; Millström, Alexandra H; Kim, Song M et al. (2018) Combined effects of intermittent hyperoxia and intermittent hypercapnic hypoxia on respiratory control in neonatal rats. Respir Physiol Neurobiol :

Showing the most recent 10 out of 199 publications