overall goal of this INBRE renewal application is to continue the facilitation of quality biomedical research activities throughout the State of Louisiana with an emphasis on building research capacity and workforce development. The Louisiana Biomedical Research Network (LBRN) has established a strong foundation for interdisciplinary and interinstitutional research, education, training, and mentoring programs focused on seven primarily undergraduate institutions (PUIs). These PUIs have been chosen as partners based on their interest and their missions' fit with one or more of the three thematic areas of the LBRN: Computational Biology, Molecular Mechanisms of Disease, and Therapeutic and Preventive Medicine. Undergraduate students from seventeen other PUIs have the opportunity to participate in the research outreach program. Faculty and students at PUIs will be mentored and supported by scientists in the flagship, LSU, and five biomedical- research-intensive institutions. A leading-edge cyberinfrastructure connects all of these units. Overlaying all of our activities will be regular metric-driven assessment of all programs, including cores, using internal and external reviewers. Major changes have been made to improve the currently successful LBRN program. These include: improvement and expansion of our cyberinfrastructure; increased interaction with existing state COBREs; and the expansion of the number of PUIs from five to seven, adding one additional historically black college. We will also partner with Louisiana's new IDeA CTR (LA CaTS) to provide more translational science research experiences for PUI faculty and students. Undergraduate research experiences will be expanded to include opportunities during the academic year. As a demonstration of their recognition of the LBRNs importance to the state, the Louisiana Board of Regents has agreed to continue to provide a match of $1.14 million for the new application. Other support from universities brings this total match to more than $2.93 million. With these improvements and this match it is clear that the LBRN will meet its goals and those of the national INBRE program.

Public Health Relevance

The Louisiana Biomedical Research Network (LBRN) is a project funded by the National Institutes of Health. LBRN provides expert educational, training, and research opportunities for undergraduate students, graduate students, and faculty at Louisiana's primarily undergraduate institutions of higher education. The result of this expanded infrastructure, educational support, and linkages with the state's research-intensive universities and institutes is new research findings that impact public health and increase Louisiana's biotechnical and biomedical workforce capacity.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Exploratory Grants (P20)
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Special Emphasis Panel (ZGM1)
Program Officer
Arora, Krishan
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Louisiana State University A&M Col Baton Rouge
Schools of Veterinary Medicine
Baton Rouge
United States
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Al-Horani, Rami A; Afosah, Daniel K (2018) Recent advances in the discovery and development of factor XI/XIa inhibitors. Med Res Rev 38:1974-2023
Singh, Dhirendra P; Kaur, Gagandeep; Bagam, Prathyusha et al. (2018) Membrane microdomains regulate NLRP10- and NLRP12-dependent signalling in A549 cells challenged with cigarette smoke extract. Arch Toxicol 92:1767-1783
Mei, Suyu; Flemington, Erik K; Zhang, Kun (2018) Transferring knowledge of bacterial protein interaction networks to predict pathogen targeted human genes and immune signaling pathways: a case study on M. tuberculosis. BMC Genomics 19:505
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