The University of Wyoming (UW) is a land-grant institution and the only baccalaureate, post-secondary degree-granting institution in the State of Wyoming. This application is a continuation of previous NCRR IDeA program awards (P20RR016474), now managed through NIGMS (GM103432-13). The long-term programmatic goal to establish a statewide network for biomedical research and excellence will be continued.
The Specific Aims for this application are to: 1) continue to build on the established multi- disciplinary research network with scientific foci that will build and strengthen biomedical research expertise and infrastructure at the University of Wyoming and its seven partner institutions; 2) build and increase the research base and capacity of the University of Wyoming and its partner institutions by providing research support to faculty, postdoctoral fellows and graduate students; 3) provide research opportunities for undergraduate students that will create a pipeline for undergraduate students to continue in health research careers within IDeA states; 4) enhance the science and technology knowledge of the state's workforce; and 5) expand Wyoming research opportunities across the Western IDeA Region. Consistent with the goal to build on past achievements and existing strengths efforts will continue to focus on acquiring a critical mass of biomedical research faculty to develop sustainable and competitive research programs as well as ways to provide opportunities for undergraduates at UW and all seven of the state's community colleges to participate in hands-on biomedical research. Three cores are proposed: Administrative, Bioinformatics, and Outreach. Because of the success of the Outreach Core and its importance to the statewide network, this core will be retained and expanded. The name of the core has been changed to Outreach and Education Core to better reflect its function. In addition, plans for a mandatory Developmental Research Project Program are describe. Two thematic research areas have been identified: 1) Cardiometabolic Syndrome and 2) Biomedical Technologies for Chronic Disease Research. The first is based on existing strengths in cardiovascular and metabolic disease (obesity/type 2 diabetes) developed during the previous INBRE that can be further improved; the second is a new thematic area. The new thematic area is the result of the collective vision of four junior faculty who have realized the value of collaboration, sharing of expertise, and building research teams to address biomedical-related problems. The Wyoming INBRE Network will be further enhanced by forming partnerships between faculty at UW and community colleges. This approach will provide role models to build links to other institutions and will be essential in moving the thematic research areas forward by increasing the quality and visibility of the research performed across the state. Finally, by creating opportunities for undergraduates early in their academic careers, a pool of students will be created that will contribute to the next generation of health professionals, biomedical scientists, and employees for the biotechnology industries.

Public Health Relevance

The Wyoming IDeA Networks for Biomedical Research Excellence (INBRE) Program is funded by the National Institutes for Health National Institute for General Medical Sciences (NIGMS). The ultimate goal of Wyoming INBRE is to work with the University of Wyoming and Wyoming's community colleges to promote the development, coordination, and sharing of research resources and expertise that will expand biomedical-related research and education opportunities and increase the number of competitive investigators in Wyoming. INBRE programs implemented are intended to enhance the caliber of scientific faculty at research institutions and undergraduate schools, thereby attracting more promising students to these organizations.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103432-14A1
Application #
8898483
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Arora, Krishan
Project Start
2001-09-30
Project End
2020-04-30
Budget Start
2015-07-01
Budget End
2016-04-30
Support Year
14
Fiscal Year
2015
Total Cost
Indirect Cost
Name
University of Wyoming
Department
Other Health Professions
Type
Schools of Pharmacy
DUNS #
069690956
City
Laramie
State
WY
Country
United States
Zip Code
82071
DeVore, Stanley B; Young, Coleman H; Li, Guangyuan et al. (2018) Histone citrullination represses miRNA expression resulting in increased oncogene mRNAs in somatolactotrope cells. Mol Cell Biol :
Joseph, Braveen B; Blouin, Nicolas A; Fay, David S (2018) Use of a Sibling Subtraction Method for Identifying Causal Mutations in Caenorhabditis elegans by Whole-Genome Sequencing. G3 (Bethesda) 8:669-678
Chi, Peter B; Kim, Dohyup; Lai, Jason K et al. (2018) A new parameter-rich structure-aware mechanistic model for amino acid substitution during evolution. Proteins 86:218-228
Milunovic-Jevtic, Ana; Jevtic, Predrag; Levy, Daniel L et al. (2018) In vivo mitotic spindle scaling can be modulated by changing the levels of a single protein: the microtubule polymerase XMAP215. Mol Biol Cell 29:1311-1317
Chen, Zhilong; Song, Jiangping; Chen, Liang et al. (2018) Characterization of TTN Novex Splicing Variants across Species and the Role of RBM20 in Novex-Specific Exon Splicing. Genes (Basel) 9:
McAllister, Chris T; Motriuk-Smith, Dagmara; Kerr, Catherine M (2018) Three new coccidians (Cyclospora, Eimeria) from eastern moles, Scalopus aquaticus (Linnaeus) (Mammalia: Soricomorpha: Talpidae) from Arkansas, USA. Syst Parasitol 95:271-279
Guo, Wei; Sun, Mingming (2018) RBM20, a potential target for treatment of cardiomyopathy via titin isoform switching. Biophys Rev 10:15-25
Hull, Noah; Miller, Jonathan; Berry, David et al. (2018) Optimization of Brucella abortus Protocols for Downstream Molecular Applications. J Clin Microbiol 56:
Giri, Basant; Liu, Yukari; Nchocho, Fidelis N et al. (2018) Microfluidic ELISA employing an enzyme substrate and product species with similar detection properties. Analyst 143:989-998
Jiang, Zhongliang; Jiang, Kun; McBride, Ralph et al. (2018) Comparative cytocompatibility of multiple candidate cell types to photoencapsulation in PEGNB/PEGDA macroscale or microscale hydrogels. Biomed Mater 13:065012

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