Abstract

The Bioinformatics Core (BC) works with the WV-INBRE Genomics Core (GC) at Marshall University (MU) and West Virginia University (WVU) GC to deliver integrated analysis of Next Generation Sequencing (NGS) and microarray data sets. NGS and microarray data analysis are and will be provided to network investigators as a full service from planning and experimental design, through DNA/RNA Quality Control (QC), wet lab experimentation with Quality Analysis (QA), data analysis and interpretation, to delivery of results, and discussion of their significance and additional methods of analysis. Under our service model, investigators must meet with BC and GC staff to discuss experimental design, methods of analysis, expected outcomes and costs prior to the initiation of any experimentation (full description of service plan is provided under section 11(3)). A separate description of the GC as an optional Core is provided as part of this application. Members of the BC and the GC work together on most of these services.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103434-14
Application #
8715992
Study Section
Special Emphasis Panel (ZGM1-TWD-7 (IN))
Project Start
Project End
2019-07-31
Budget Start
2014-09-19
Budget End
2015-07-31
Support Year
14
Fiscal Year
2014
Total Cost
$314,750
Indirect Cost
$27,691

  Institution

Name
Marshall University
Department
Type
DUNS #
036156615
City
Huntington
State
WV
Country
United States
Zip Code
25701

  Publications

Perla, Venu; Nadimi, Marjan; Reddy, Rishi et al. (2018) Effect of ghost pepper on cell proliferation, apoptosis, senescence and global proteomic profile in human renal adenocarcinoma cells. PLoS One 13:e0206183
Boehm, Dylan T; Hall, Jesse M; Wong, Ting Y et al. (2018) Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice. Infect Immun 86:
Zhang, Yu; Chen, Shiguo; Wei, Chaoyang et al. (2018) Dietary compound proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves attenuate chemotherapy-resistant ovarian cancer stem cell traits via targeting the Wnt/?-catenin signaling pathway and inducing G1 cell cycle arrest. Food Funct 9:525-533
Zdilla, Matthew J; Russell, Michelle L; Koons, Aaron W (2018) Infraorbital foramen location in the pediatric population: A guide for infraorbital nerve block. Paediatr Anaesth 28:697-702
Shumar, Stephanie A; Kerr, Evan W; Geldenhuys, Werner J et al. (2018) Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform. J Biol Chem 293:4134-4148
Gao, Ying; Yin, Junfeng; Rankin, Gary O et al. (2018) Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells. Molecules 23:
Friedman, Jamie R; Nolan, Nicholas A; Brown, Kathleen C et al. (2018) Anticancer Activity of Natural and Synthetic Capsaicin Analogs. J Pharmacol Exp Ther 364:462-473
Bedenbaugh, M N; O'Connell, R C; Lopez, J A et al. (2018) Kisspeptin, gonadotrophin-releasing hormone and oestrogen receptor ? colocalise with neuronal nitric oxide synthase neurones in prepubertal female sheep. J Neuroendocrinol 30:
Pan, Haibo; Li, Jin; Rankin, Gary O et al. (2018) Synergistic effect of black tea polyphenol, theaflavin-3,3'-digallate with cisplatin against cisplatin resistant human ovarian cancer cells. J Funct Foods 46:1-11
Mays Jr, Herman L; Hung, Chih-Ming; Shaner, Pei-Jen et al. (2018) Genomic Analysis of Demographic History and Ecological Niche Modeling in the Endangered Sumatran Rhinoceros Dicerorhinus sumatrensis. Curr Biol 28:70-76.e4

Showing the most recent 10 out of 207 publications