Abstract

Bioinformatics Core The Bioinformatics Core, based at the University of Louisville Health Science Campus, is designed to serve the bioinformatics needs of faculty and students within KBRIN-affiliated institutions. A specific focus is placed on DNA and RNA sequence analysis (i.e. ?Genomics? and ?Transcriptomics?), with an expertise in the field of high- throughput genomic and transcriptomic data resulting from array-based and high-throughput sequencing technologies. We have developed the core through recruitment of expert faculty and postdoctoral level research associates so as to quickly build a capacity for bioinformatics research, as well as, to provide service and collaboration with biomedical research scientists. In addition, the core provides multiple levels of student training activities. We will continue to pursue those activities that lead to excellence in this rapidly evolving scientific arena.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103436-20
Application #
9917797
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
20
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
University of Louisville
Department
Type
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40292

  Publications

Colter, Breann T; Garber, Helen Frances; Fleming, Sheila M et al. (2018) Ahr and Cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls. Neurotoxicology 65:125-134
Marczinski, Cecile A; Stamates, Amy L; Maloney, Sarah F (2018) Differential development of acute tolerance may explain heightened rates of impaired driving after consumption of alcohol mixed with energy drinks versus alcohol alone. Exp Clin Psychopharmacol 26:147-155
Lee, Juyeun; Park, Nogi; Park, Joo Youn et al. (2018) Induction of Immunosuppressive CD8+CD25+FOXP3+ Regulatory T Cells by Suboptimal Stimulation with Staphylococcal Enterotoxin C1. J Immunol 200:669-680
King, Rodney A; Perez, Meghan T (2018) Sequence Analysis of a Hybrid HK022/? Bacteriophage and the Precise Identification of the ?b515 and ?b519 Deletion Endpoints. Microbiol Resour Announc 7:
Gonzalez, O A; Kirakodu, S; Novak, M J et al. (2018) Comparative analysis of microbial sensing molecules in mucosal tissues with aging. Immunobiology 223:279-287
Ha, Dat Thinh; Ghosh, Sthitodhi; Ahn, Chong H et al. (2018) Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip. Analyst 143:4009-4016
Song, Ming; Li, Xiaohong; Zhang, Xiang et al. (2018) Dietary copper-fructose interactions alter gut microbial activity in male rats. Am J Physiol Gastrointest Liver Physiol 314:G119-G130
Yates, Justin R; Gunkel, Benjamin T; Rogers, Katherine K et al. (2018) Effects of N-methyl-d-aspartate receptor (NMDAr) uncompetitive antagonists in a delay discounting paradigm using a concurrent-chains procedure. Behav Brain Res 349:125-129
Carlson, Katy; Tyler, Joseph C (2018) Accents, Not Just Prosodic Boundaries, Influence Syntactic Attachment. Lang Speech 61:246-276
Weber, Gregory J; Foster, Jaleyea; Pushpakumar, Sathnur B et al. (2018) Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized with hydrogen sulfide supplementation. Pharmacol Res 134:157-165

Showing the most recent 10 out of 193 publications