SD BRIN was able to provide Alterations and Renovations support to two of the partner PUIs during Phase II of INBRE in 2009 which greatly facilitated the remodeling project for the new location of the WestCore DNA Sequencing and Genotyping Core Facility at BHSU and paid for the extension of electrical capacity into the remodeled library building for new research space at MMC. With this proposal, two other PUI partners have need of modeling for their remodeling projects. Augustana College is building a large addition to Gilbert Science Center (GSC) to house a number of research laboratories and nearby teaching laboratories. The proposed project will create a 693 sq.ft. vivarium to house vertebrate and invertebrate animals and provide research space on the first floor of the new West Wing of the GSC. In addition to the remodeled space, changes will be required for air circulation, lack of good ventilation, and lack of power for scientific equipment. The planned vivarium will allow collaborative projects among various faculty members to be conducted in shared space which meets modern standards and codes. The University of Sioux Falls needs to remodel for a separate Chemistry Analytical Research Laboratory on the third floor of the Salisbury Science Center (remodeled during Phase II of INBRE with institutional funds to include research laboratories). The Alterations and Renovations funds will help establish a separate, safe, chemical analysis core facility with additional storage to be used by Dr. Mwangi and his undergraduate research fellows without interfering with other research areas. The equipment in the space will be more efficiently arranged and new fume hoods will be installed. Dr. Mwangi has mentored 3-4 undergraduate fellows annually who help with his research. Both of these requests require financial investments from the institutions to complete the projects. These A&R funds will assist these PUI partners in improving their research infrastructure and supplement the efforts of each institution in building new research space for their faculty and student researchers.

Public Health Relevance

Alterations and Renovations Narrative SD BRIN is requesting $250,000 in alterations and renovations funding to assist two of our partner predominantly undergraduate institutions in completing and improving their research space. Augustana College is building an addition to their science building and needs to remodel for new vivarium space to house vertebrate and invertebrate animals to be used in research. University of Sioux Falls will be improving research space to build a Chemistry Analytical Core Facility to better separate the analytical chemistry experiments from other research space.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103443-14A1
Application #
8897717
Study Section
Special Emphasis Panel (ZGM1-TWD-0 (IN))
Project Start
Project End
Budget Start
2015-07-15
Budget End
2016-04-30
Support Year
14
Fiscal Year
2015
Total Cost
$249,999
Indirect Cost
Name
University of South Dakota
Department
Type
DUNS #
929930808
City
Vermillion
State
SD
Country
United States
Zip Code
57069
Bosch, T J; Hanna, T; Fercho, K A et al. (2018) Behavioral performance and visual strategies during skill acquisition using a novel tool use motor learning task. Sci Rep 8:13755
Anderson, Ruthellen H; Lensing, Cody J; Forred, Benjamin J et al. (2018) Differentiating Antiproliferative and Chemopreventive Modes of Activity for Electron-Deficient Aryl Isothiocyanates against Human MCF-7 Cells. ChemMedChem 13:1695-1710
Klonoski, Joshua M; Watson, Trevor; Bickett, Thomas E et al. (2018) Contributions of Influenza Virus Hemagglutinin and Host Immune Responses Toward the Severity of Influenza Virus: Streptococcus pyogenes Superinfections. Viral Immunol 31:457-469
Dosch, John; Hadley, Elise; Wiese, Cal et al. (2018) Time-lapse microscopic observation of non-dividing cells in cultured human osteosarcoma MG-63 cell line. Cell Cycle 17:174-181
Liang, Ashley Paula; Drazick, Anthony Thomas; Gao, Hongbo et al. (2018) Skeletal muscle secretion of IL-6 is muscle type specific: Ex vivo evidence. Biochem Biophys Res Commun 505:146-150
Herrera, Andrea L; Faal, Haddy; Moss, Danielle et al. (2018) The Streptococcus pyogenes fibronectin/tenascin-binding protein PrtF.2 contributes to virulence in an influenza superinfection. Sci Rep 8:12126
Grausam, Katie B; Dooyema, Samuel D R; Bihannic, Laure et al. (2017) ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas. Cancer Res 77:3766-3777
Madison, Joseph D; Berg, Elizabeth A; Abarca, Juan G et al. (2017) Characterization ofBatrachochytrium dendrobatidisInhibiting Bacteria from Amphibian Populations in Costa Rica. Front Microbiol 8:290
Messerli, Shanta M; Hoffman, Mariah M; Gnimpieba, Etienne Z et al. (2017) Therapeutic Targeting of PTK7 is Cytotoxic in Atypical Teratoid Rhabdoid Tumors. Mol Cancer Res 15:973-983
Messerli, Shanta M; Hoffman, Mariah M; Gnimpieba, Etienne Z et al. (2017) 4SC-202 as a Potential Treatment for the Pediatric Brain Tumor Medulloblastoma. Brain Sci 7:

Showing the most recent 10 out of 64 publications