Defining the DE-INBRE Network of Cores There are four original DE-INBRE-funded cores located at the DBI. Their success has lead to salary, service ?contract, and equipment funding from DE-INBRE, DE-EPSCoR, COBRE, institutional support and individual NIH and NSF research grants. In order to increase the breadth of technologies available to DE-INBRE researchers, a Network of cores (referred to as DE-INBRE-affiliated centers) was established whose activitiesare coordinated through the CRIC. The DE-INBRE-2 has seen increased participation of cores from within UD /DBl as well as two of our partner institutions including Nemours and Christiana Care Health Services (CCHS). DE-INBRE-3 will support even more expansion with the establishment of two new Cores in joint collaboration with Delaware State University?(DSV) as described in Section 6.4.2. The current DE-INBRE? affiliated centers include 11 technology cores and are led by accomplished Directors (see credentials below) . and skilled professional staff (listed in the Resource Section of this application. DE-INBRR-affiliated centers operate under a collaborative or fee-for-service model or a combination thereof. DE-INBRE operating guidelines:The cores """"""""internal pricing"""""""" fee structures are in accordance with government policies and include charges that are allowable, reasonable and allocable in relation to cost of services. When appropriate, as for external pricing, an additional overhead surcharge is included. Fee-for? services may be subsidized to diverse degrees by the core's DE-INBRE home institution. These institutional subsidies demonstrate the strong commitment of the DE-INBRE partners to maintaining accessibility of the technologies to INBRE/COBRE and internally funded investigators. Each DE-INBRE-affiliated center has implemented equipment usage policies and standard operating procedures that provide consistent accessibility to the services. The professional, staff conduct scheduled instrumentation maintenance to ensure equipment is operating within specification for high quality data assurance. Additionally, instruments covered by service contracts receive preventative maintenance at least once a year. Services are available for all users on a first come first serve basis. A complete listing of the core technologies Iinstrumentations is included in the Resource Section.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103446-14
Application #
8716070
Study Section
Special Emphasis Panel (ZGM1-TWD-3 (IN))
Project Start
Project End
2019-04-30
Budget Start
2014-08-01
Budget End
2015-04-30
Support Year
14
Fiscal Year
2014
Total Cost
$971,691
Indirect Cost
$137,502
Name
University of Delaware
Department
Type
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716
Allgood, Samual C; Neunuebel, M Ramona (2018) The recycling endosome and bacterial pathogens. Cell Microbiol 20:e12857
Franke, Karl R; Schmidt, Skye A; Park, Sunhee et al. (2018) Analysis of Brachypodium miRNA targets: evidence for diverse control during stress and conservation in bioenergy crops. BMC Genomics 19:547
Huang, Lei; Liao, Li; Wu, Cathy H (2018) Completing sparse and disconnected protein-protein network by deep learning. BMC Bioinformatics 19:103
Kevill, Dennis Neil; Kim, Chang-Bae; D'Souza, Malcolm John (2018) Correlation of the rates of solvolysis of ?-bromoisobutyrophenone using both simple and extended forms of the Grunwald-Winstein equation and the application of correlation analysis to related studies. Eur J Chem 9:1-6
Lemmon, Elisabeth A; Locke, Ryan C; Szostek, Adrianna K et al. (2018) Partial-width injuries of the rat rotator cuff heal with fibrosis. Connect Tissue Res 59:437-446
Phay, Monichan; Kim, Hak Hee; Yoo, Soonmoon (2018) Analysis of piRNA-Like Small Non-coding RNAs Present in Axons of Adult Sensory Neurons. Mol Neurobiol 55:483-494
Modarai, Shirin R; Gupta, Anindita; Opdenaker, Lynn M et al. (2018) The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells. Oncotarget 9:34658-34669
Hellbach, Nicole; Peterson, Suzanne; Haehnke, Daniel et al. (2018) Impaired myogenic development, differentiation and function in hESC-derived SMA myoblasts and myotubes. PLoS One 13:e0205589
DeMeester, Kristen E; Liang, Hai; Jensen, Matthew R et al. (2018) Synthesis of Functionalized N-Acetyl Muramic Acids To Probe Bacterial Cell Wall Recycling and Biosynthesis. J Am Chem Soc 140:9458-9465
Modarai, Shirin R; Man, Dula; Bialk, Pawel et al. (2018) Efficient Delivery and Nuclear Uptake Is Not Sufficient to Detect Gene Editing in CD34+ Cells Directed by a Ribonucleoprotein Complex. Mol Ther Nucleic Acids 11:116-129

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