? Bioinformatics Core Bioinformatics now plays a central role in supporting research in biomedical and all life sciences; data-intensive research methodologies like RNA sequencing have become foundational techniques. The researchers of today must have a grasp of the concepts for how these technologies can advance their research. To support the growing and diversified informatics needs, bioinformatics cores have to evolve to not only provide computational infrastructure and the expertise to perform high-throughput data analysis, but also increasingly to serve as centers of education driving the training of informatically savvy researchers who can effectively utilize and interpret the data. Having built strong foundations for bioinformatics resources in Delaware under previous DE-INBRE funding cycles, the Bioinformatics Core will further expand its reach and impact throughout the State. The DE-INBRE Bioinformatics Core is organized as a Bioinformatics Network of Delaware (BiND) with a Steering Committee that includes representatives from all Partner Institutions to help guide and shape Delaware INBRE?s bioinformatics initiatives and create synergies to meet the evolving needs of the program. In particular, DE-INBRE IV will increase accessibility of bioinformatics resources and expertise currently concentrated at University of Delaware (UD), bio-imaging and computational neuroscience at Delaware State University (DSU), and biomedical and clinical informatics resources housed at Nemours/Alfred I. duPont Hospital for Children (Nemours) and Christiana Care Health System (CCHS) among the DE-INBRE Partner Institutions to provide the informatics cyberinfrastructure, research support, educational programs, and research exposures needed to promote a vibrant biomedical research capacity in the State of Delaware.
Specific Aims 1. Support DE-INBRE?s expanded Biomedical Research Network. 2. Enhance Delaware?s biomedical research capacity. 3. Support biomedical research initiatives in Delaware. 4. Enhance the science and technology knowledge of Delaware?s workforce.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103446-20
Application #
9930650
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
20
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Delaware
Department
Type
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716
Vest, Michael T; Papas, Mia A; Shapero, Mary et al. (2018) Characteristics and Outcomes of Adult Inpatients With Malnutrition. JPEN J Parenter Enteral Nutr 42:1009-1016
Minker, Katharine R; Biedrzycki, Meredith L; Kolagunda, Abhishek et al. (2018) Semiautomated confocal imaging of fungal pathogenesis on plants: Microscopic analysis of macroscopic specimens. Microsc Res Tech 81:141-152
Papah, Michael B; Brannick, Erin M; Schmidt, Carl J et al. (2018) Gene expression profiling of the early pathogenesis of wooden breast disease in commercial broiler chickens using RNA-sequencing. PLoS One 13:e0207346
Goyal, Ritu; Kapadia, Chintan H; Melamed, Jilian R et al. (2018) Layer-by-layer assembled gold nanoshells for the intracellular delivery of miR-34a. Cell Mol Bioeng 11:383-396
Hudson, Devin A; Caplan, Jeffrey L; Thorpe, Colin (2018) Designing Flavoprotein-GFP Fusion Probes for Analyte-Specific Ratiometric Fluorescence Imaging. Biochemistry 57:1178-1189
Cogburn, Larry A; Trakooljul, Nares; Chen, Chuming et al. (2018) Transcriptional profiling of liver during the critical embryo-to-hatchling transition period in the chicken (Gallus gallus). BMC Genomics 19:695
Graham, Brian T; Moore, Axel C; Burris, David L et al. (2018) Mapping the spatiotemporal evolution of solute transport in articular cartilage explants reveals how cartilage recovers fluid within the contact area during sliding. J Biomech 71:271-276
Çelen, ?rem; Doh, Jung H; Sabanayagam, Chandran R (2018) Effects of liquid cultivation on gene expression and phenotype of C. elegans. BMC Genomics 19:562
D'Souza, Malcolm J; Bautista, Riza C; Wentzien, Derald E (2018) Data Talks: Obesity-Related Influences on US Mortality Rates. Res Health Sci 3:65-78
Siddam, Archana D; Gautier-Courteille, Carole; Perez-Campos, Linette et al. (2018) The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development. PLoS Genet 14:e1007278

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