The Mississippi IDeA Networks of Biomedical Research Excellence (MS-INBRE) has the mission to enhance biomedical research and student training across the entire state of Mississippi. Unfortunately, Mississippi suffers from the worst overall health in the nation and a historically low investment in biomedical research and training and STEM education to develop the very workforce of skilled individuals who could address these problems. The three specific aims of the MS-INBRE are designed to help reverse this trend and develop a cadre of talented and dedicated biomedical researchers, clinicians, scientists, educators, policy makers, etc. to address these issues.
Aim 1 : continue to build and strengthen biomedical research labs at six Partner Undergraduate Institutions (PUI; Alcorn State University, Millsaps College, Mississippi College, Mississippi University for Women, Mississippi Valley State University and Tougaloo College) to facilitate research and student training. Five new tenure-track hires will be added to build their research and student training capacity. Research mentors will assist them to develop research projects in Obesity, Cancer and STDs. The Bioinformatics Core will facilitate incorporation of informatics approaches into their research. Three core facilities (Imaging, Genomics, Proteomics) will be available to facilitate thi research, PUI faculty will have professional development training in grant writing, manuscript writing, etc. to help develop sustainable research and student training programs.
Aim 2 : develop a workforce to address the State's health issues via an efficient student pipeline into health-related careers. We will continue our highly successful undergraduate summer research intemship (MIRS, MS INBRE Research Scholars) to give students (particularly underrepresented minorities) intensive hands-on research training and health-related career counseling.
Aim 3 : develop a new Community Engagement and Training Core which will train students in community education, outreach, etc. which will reach the most impoverished and underserved areas in Mississippi. The MS-INBRE will enhance biomedical research today and reach into the next generation as we train the researchers, physicians, health-workers, policy-makers, etc. of the future.

Public Health Relevance

Mississippi suffers from the worst health in the nation, particularly with extremely high rates of obesity, cancer and STDs. It is essential that we reverse this trend by developing a strong foundation in biomedical research and student training/workforce development. These students will be the future doctors, biomedical researchers, scientists, science teachers, etc. to help address these terrible health problems and create a brighter future for the State.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
4P20GM103476-15
Application #
9115626
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Alexander, Rashada
Project Start
2001-09-20
Project End
2018-05-31
Budget Start
2016-06-01
Budget End
2017-05-31
Support Year
15
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Southern Mississippi
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
623335775
City
Hattiesburg
State
MS
Country
United States
Zip Code
39406
Mahajan, Gouri J; Vallender, Eric J; Garrett, Michael R et al. (2018) Altered neuro-inflammatory gene expression in hippocampus in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 82:177-186
Adhikari, Pratikshya; Xu, Hao (2018) PKC-dependent phosphorylation of Munc18a at Ser313 in activated RBL-2H3 cells. Inflamm Res 67:1-3
Wallace, Kedra; Bean, Cynthia; Bowles, Teylor et al. (2018) Hypertension, Anxiety, and Blood-Brain Barrier Permeability Are Increased in Postpartum Severe Preeclampsia/Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome Rats. Hypertension 72:946-954
Tull, Matthew T; Lee, Aaron A; Geers, Andrew L et al. (2018) Exploring the Role of Sedentary Behavior and Physical Activity in Depression and Anxiety Symptom Severity among Patients with Substance Use Disorders. Ment Health Phys Act 14:98-102
Rangachari, Vijayaraghavan; Dean, Dexter N; Rana, Pratip et al. (2018) Cause and consequence of A? - Lipid interactions in Alzheimer disease pathogenesis. Biochim Biophys Acta Biomembr :
Parsons, Keith H; Mondal, Mosharrof H; McCormick, Charles L et al. (2018) Guanidinium-Functionalized Interpolyelectrolyte Complexes Enabling RNAi in Resistant Insect Pests. Biomacromolecules 19:1111-1117
Turner, Paul A; Garrett, Michael R; Didion, Sean P et al. (2018) Spheroid Culture System Confers Differentiated Transcriptome Profile and Functional Advantage to 3T3-L1 Adipocytes. Ann Biomed Eng 46:772-787
Amato, Douglas V; Amato, Dahlia N; Blancett, Logan T et al. (2018) A bio-based pro-antimicrobial polymer network via degradable acetal linkages. Acta Biomater 67:196-205
D'Angelo, William; Chen, Bohan; Gurung, Chandan et al. (2018) Characterization of embryonic stem cell-differentiated fibroblasts as mesenchymal stem cells with robust expansion capacity and attenuated innate immunity. Stem Cell Res Ther 9:278
Mavrodi, Dmitri V; Mavrodi, Olga V; Elbourne, Liam D H et al. (2018) Long-Term Irrigation Affects the Dynamics and Activity of the Wheat Rhizosphere Microbiome. Front Plant Sci 9:345

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