The Center for Brain Recovery and Repair will be transformative for brain injury research at UNM. It will address a critical gap that currently exists by generating a well-funded, interdisciplinary group of investigators concentrating on effective and relevant interventions for survivors of acute brain injuries, including stroke and traumatic brain injury. The Center will provide state-of-the-art equipment, training, technical expertise, and significant project support to elevate multiple new projects to the level of RO1 funding. An effective and motivated Administrative Core is essential to the success of these different activities, and for developing a cohesive community of investigators who will work together to grow and sustain the Center, and meet IDeA program goals. The Administrative Core's activities will be focused on three main aims: 1) to provide scientific direction and program support 2) to coordinate research training and career development of a cohort of promising junior investigators and 3) to develop a sustainable community of brain recovery and repair investigators. The Core's leadership and oversight committees will provide the overall scientific direction, fiscal management and strategic planning for the center. The Core includes rigorous evaluation and feedback activities, which will track progress of all components, and be used to make program adjustments to increase the impact and sustainability of the Center. Mentoring and research training will be coordinated by the Core, with approaches that include initial needs assessments and oversight of training plans and progress of mentees, as well as training and evaluation of mentors. Finally, the Core will coordinate seminars, training programs, technical workshops and interactions with brain injury programs in the community, that are all essential to providing a rich intellectual environment for all participants in the Center. The Administrative Core will also facilitate interactions with other programs and cores, to improve training opportunities and access to facilities for Center investigators and colleagues at UNM and other IDeA program sites. Achieving these aims will provide the foundation for a concerted and sustained effort by talented investigators with different backgrounds to work together to develop new interventions for those living with the consequences of acute brain injury.

Public Health Relevance

The Center for Brain Recovery and Repair will generate a critical mass of investigators, utilizing new resources to develop effective treatments for survivors of acute brain injury, including stroke and traumatic brain injury. The Administrative Core will provide the leadership and oversight to ensure success of the Center, to provide the basis for sustained success of Center and improvements in NM health.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
1P20GM109089-01A1
Application #
8813361
Study Section
Special Emphasis Panel (ZGM1-TWD-0)
Project Start
Project End
Budget Start
2015-09-15
Budget End
2016-06-30
Support Year
1
Fiscal Year
2015
Total Cost
$426,710
Indirect Cost
$140,774
Name
University of New Mexico Health Sciences Center
Department
Type
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Bragin, Denis E; Bragina, Olga A; Hagberg, Sean et al. (2018) Pulsed Electromagnetic Field (PEMF) Mitigates High Intracranial Pressure (ICP) Induced Microvascular Shunting (MVS) in Rats. Acta Neurochir Suppl 126:93-95
Bragin, Denis E; Statom, Gloria L; Nemoto, Edwin M (2018) Induced Dynamic Intracranial Pressure and Cerebrovascular Reactivity Assessment of Cerebrovascular Autoregulation After Traumatic Brain Injury with High Intracranial Pressure in Rats. Acta Neurochir Suppl 126:309-312
Rowland, Andrew S; Gorman, Stephanie A; Thoma, Robert J et al. (2018) Rowland et al. Respond. Am J Public Health 108:e12-e13
Robinson, Shenandoah; Winer, Jesse L; Chan, Lindsay A S et al. (2018) Extended Erythropoietin Treatment Prevents Chronic Executive Functional and Microstructural Deficits Following Early Severe Traumatic Brain Injury in Rats. Front Neurol 9:451
Carlson, Andrew P; Abbas, Mohammad; Alunday, Robert L et al. (2018) Spreading depolarization in acute brain injury inhibited by ketamine: a prospective, randomized, multiple crossover trial. J Neurosurg :1-7
Reinhart, Katelyn M; Shuttleworth, C William (2018) Ketamine reduces deleterious consequences of spreading depolarizations. Exp Neurol 305:121-128
Gasparovic, Charles; Caprihan, Arvind; Yeo, Ronald A et al. (2018) The long-term effect of erythropoiesis stimulating agents given to preterm infants: a proton magnetic resonance spectroscopy study on neurometabolites in early childhood. Pediatr Radiol 48:374-382
Oliver, R J; Brigman, J L; Bolognani, F et al. (2018) Neuronal RNA-binding protein HuD regulates addiction-related gene expression and behavior. Genes Brain Behav 17:e12454
Mayer, Andrew R; Wertz, Christopher; Ryman, Sephira G et al. (2018) Neurosensory Deficits Vary as a Function of Point of Care in Pediatric Mild Traumatic Brain Injury. J Neurotrauma 35:1178-1184
Quinn, Davin K; Mayer, Andrew R; Master, Christina L et al. (2018) Prolonged Postconcussive Symptoms. Am J Psychiatry 175:103-111

Showing the most recent 10 out of 46 publications