The goal of this application is to develop an integrated, interdisciplinary and translational Center for Childhood Obesity Prevention. Childhood obesity is a national public health threat that is disproportionately worse in Arkansas. Therefore, the immediate goal is to prevent the rise in Arkansas childhood obesity rates, with an ultimate goal of reducing childhood obesity rates by ?10% (reduction of ~3.8%) in our state over the next 5-10 years. Through the establishment of the Center, we will meet this critical need through a coordinated, community-based approach targeting modifiable individual risk behaviors, environmental risk factors, and local, state and national risk reduction policies. This strategy will include investigation of underlying metabolic factors. We will bring together a group of four promising junior investigators whose collective research focuses on multiple aspects of this central theme, provide these investigators with a supportive infrastructure environment developed specifically to enhance their chances for success, and use the foundation provided by this initial group to develop four additional pipeline junior investigators, as well as to promoe ongoing recruitment of subsequent junior investigators with an interest in community-based approaches to childhood obesity prevention.
Specific Aim #1 will establish the Center for Childhood Obesity Prevention, addressing childhood obesity through targeted behaviors, environments, and policies.
In Specific Aim #2, we will coordinate and enhance existing research infrastructure and collaboration throughout the ACHRI and the UA System in support of the Center. Three cores will be established or enhanced to support the research of Center investigators: an Administrative and Scientific Support Core A, a Biostatistics and Informatics Core B, and a Metabolism Core C, each under the leadership of experienced senior faculty with strong research and administrative backgrounds. The mentoring program will consist of the Center Mentoring Committee (CMC) which includes two senior faculty members matched with each junior investigator and each pipeline investigator (11 total; some overlap); further, the UAMS Faculty Development Program (FDP) supports the general academic career development and advancement of junior faculty through the Promotion and Tenure process. These strategies, in coordination with the expertise of the established senior research faculty and an internal Executive Committee, will provide the synergy and oversight required for the development of ongoing successful external applications to sustain this work.

Public Health Relevance

Childhood obesity is national public health threat, with obesity rates in Arkansas higher than the national average. Through the establishment of a Center to manage a coordinated, community-based approach targeting modifiable individual risk behaviors, environmental risk factors, and state and national risk reduction policies, we seek to first prevent the rise in childhood obesity rates, then ultimately reduce obesity rates by ?10% (reduction of ~3.8%) in Arkansas over the next 5 to 10 years.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
1P20GM109096-01A1
Application #
8813133
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Canto, Maria Teresa
Project Start
2016-08-01
Project End
2021-07-31
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
1
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Arkansas Children's Hospital Research Institute
Department
Type
DUNS #
002593692
City
Little Rock
State
AR
Country
United States
Zip Code
72202