The goal of the COBRE Center for Redox Biology and Cardiovascular Disease is to establish a nationally recognized advanced research and training program that facilitates the development of junior faculty research toward major independent research funding in the research intersections between redox biology and cardiovascular disease. In order to accomplish this goal, a multifaceted plan for research program development along with mentorship and training is required. The Administration Core A will implement and manage all COBRE program initiatives including establishing advanced research core facilities, establishing a mentorship program for junior faculty development, establishing External and Internal Advisory Committees along with a Senior Mentoring Committee, establishing an annual scientific colloquium and formal evaluation procedures, and establishing pilot grant mechanism that supports development of promising projects from junior faculty. The Administration Core will managed by the COBRE PI along with coordinator assistance, clinical research coordination, and business management oversight of the program budget. This core will centralize all COBRE program documentation and reporting in compliance with NIH COBRE requirements.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM121307-03
Application #
9853033
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2020-02-01
Budget End
2021-01-31
Support Year
3
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Louisiana State University Hsc Shreveport
Department
Type
DUNS #
095439774
City
Shreveport
State
LA
Country
United States
Zip Code
71103
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Shrestha, Bandana; Prasai, Priya K; Kaskas, Amir M et al. (2018) Differential arterial and venous endothelial redox responses to oxidative stress. Microcirculation 25:e12486
Prasai, Priya K; Shrestha, Bandana; Orr, A Wayne et al. (2018) Decreases in GSH:GSSG activate vascular endothelial growth factor receptor 2 (VEGFR2) in human aortic endothelial cells. Redox Biol 19:22-27
Al-Yafeai, Zaki; Yurdagul Jr, Arif; Peretik, Jonette M et al. (2018) Endothelial FN (Fibronectin) Deposition by ?5?1 Integrins Drives Atherogenic Inflammation. Arterioscler Thromb Vasc Biol 38:2601-2614