This Competitive renewal application for the Center for Native and Pacific Health Disparities Research (CNPHDR or Center;P20 MD 000173) seeks 5 years of additional funding to develop a new paradigm for advancing the science of health disparities research using community engagement and empowerment to eliminate health disparities and the promotion of health equity. Our scientific theme will remain cardiometabolic health disparities among our priority populations of Native (Alaska Native, Native Hawaiians, New Zealand Maori) and Pacific Peoples (Pacific Islanders, Micronesians, Filipinos). The major focus of research investigation will include clinical, health services, interventional and translational research designs. The Center consists of 4 Cores (Research, Training and Education, Community Engagement and Administrative) and 2 Research Subprojects. Sub-project #1:
Aims to examine racial/ethnic differences in the prevalence and cost of preventable hospitalizations due to heart disease and diabetes and to use this health administrative data to pilot test a hospital-based intervention to prevent re-hospitalization. Sub-Project #2:
Aims to characterize the prevalence of intracerebral hemorrhage (ICH) and associated risk factors in the largest stroke center in the State. Initial results will then be used to inform a randomized contro trial to test a patient navigator program to improve prognosis and health related quality of life and post-stroke depression. The success of the overall CNPHDR hinges on the success of the individual cores to meet the OVERALL AIMS as follows:
Aim#1 : Design and implement health and health care disparities research studies of high impact to our priority populations.
Aim#2 : Build and train a diverse scientific workforce to actively participate in the health disparities research enterprise.
Aim#3 : Advance community engagement research approaches to strengthen participation of diverse communities in the research process and to empower communities to take action towards meaningful improvement in their own health and wellness.
Aim#4 : Integrate and centralize Native and Pacific Peoples health disparities research for the purpose of developing a new interdisciplinary science aimed at the elimination of health disparities and the promotion of health equity. The Center's proposal has many strengths: 1) It's organizational infrastructure is innovative in its approach to embrace community empowerment and engagement as the means to engender community participation in the research process and to build trust. 2) It's unique contribution to understanding cardiometabolic health disparities in 3 Native populations in the Pacific region. 3) Its commitment to build and train a diverse scientific workforce. 4) Its focus to synergize resources to stimulate a new paradigm of interdisciplinary health disparities science. 5) To prepare and empower our diverse Native and Pacific People communities to take ownership of their own health and wellness.

Public Health Relevance

Heart disease, obesity, and diabetes effect Native Hawaiians, Alaska Native, Pacific Peoples (Pacific Islanders, Micronesian and Filipinos), and New Zealand (NZ) Maoris more than other populations. This proposal will provide resources for research studies, training and educating scientists and community partners, and will work on reducing these diseases.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Exploratory Grants (P20)
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Special Emphasis Panel (ZMD1-RN (01))
Program Officer
Mcclure, Shelia A
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University of Hawaii
Internal Medicine/Medicine
Schools of Medicine
United States
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Nakagawa, Kazuma; King, Sage L; Seto, Todd B et al. (2018) Disparities in Functional Outcome After Intracerebral Hemorrhage Among Asians and Pacific Islanders. Front Neurol 9:186
Nakagawa, Kazuma; King, Sage L; Seto, Todd B (2018) Optimal Hematoma Volume Cut Points to Predict Functional Outcome After Basal Ganglia and Thalamic Hemorrhages. Front Neurol 9:291
Sentell, Tetine; Ahn, Hyeong Jun; Miyamura, Jill et al. (2018) Thirty-Day Inpatient Readmissions for Asian American and Pacific Islander Subgroups Compared With Whites. Med Care Res Rev 75:100-126
Hulgan, Todd; Ramsey, Benjamin S; Koethe, John R et al. (2018) Relationships between Adipose Mitochondrial Function, Serum Adiponectin, and Insulin Resistance in Persons with HIV after 96 weeks of Antiretroviral Therapy. J Acquir Immune Defic Syndr :
Nakagawa, Kazuma; Seto, Todd B (2018) Thrombus ""Squeezing"" Through Patent Foramen Ovale After Traumatic Brain Injury. Neurocrit Care :
Malabed, Jhon Michael; Taira, Deborah A; Seto, Todd B et al. (2018) 2017 Writing Contest Undergraduate Winner: Pathways to Preventable Hospitalizations for Filipino Patients with Diabetes and Heart Disease in Hawai'i. Hawaii J Med Public Health 77:155-160
Sentell, Tetine Lynn; Shen, Chengli; Landsittel, Doug et al. (2018) Racial/Ethnic Differences in Those Accompanying Medicare Patients to the Doctor: Insights from the 2013 Medicare Current Beneficiary's Survey. J Immigr Minor Health 20:776-783
Seto, Jason; Davis, James; Taira, Deborah Ann (2018) Examining the Association Between Different Aspects of Socioeconomic Status, Race, and Disability in Hawaii. J Racial Ethn Health Disparities 5:1247-1253
Wey, Andrew; Davis, James; Juarez, Deborah Taira et al. (2018) Distinguishing between primary and secondary racial identification in analyses of health disparities of a multiracial population in Hawaii. Ethn Health 23:233-248
Kaholokula, Joseph Keawe'aimoku; Ing, Claire Townsend; Look, Mele A et al. (2018) Culturally responsive approaches to health promotion for Native Hawaiians and Pacific Islanders. Ann Hum Biol 45:249-263

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