The long term goal of RIMI at North Carolina A&T State University is to enhance the biomedical and behavioral research and research training capacity in areas that address health disparities. This RIMI renewal builds upon the strengths and accomplishments of the first round of RIMI that created basic infrastructure in genetics research. Therefore, North Carolina A&T State University submits this competing renewal application based upon the first five years of reflective evaluation and tangible progress in enhancing research infrastructure in health disparities. The strength of this renewal application is the emphasis on developing collaborative junior faculty members, as well as students, to become independent researchers and thought leaders in eliminating health disparities. Objectives of this renewal application are to: 1) Create a focused environment in which minority students remain in the biomedical science pipeline and become thought leaders for eliminating health disparities 2) Create a mentored and collaborative environment for health disparities research 3) Develop a centralized community model for educating minorities about health disparities and for recruiting minorities into health disparities research and 4) enhance the administrative, technical and research resources that facilitate health disparities research. This project will develop a research niche in cancer biology, develop a core facility for genomics and informatics research tools, develop a core resource for subject ascertainment and education outreach, enrich student training and development through a bridge to the Masters, and provide meaningful assessment and feed back to developing researchers. The project will utilize all five of the core emphasis areas: 1) Administrative Infrastructure, 2) Faculty Research and Development, 3) Research Facilities and Technology 4) Academic Enrichment and 5) Shared Resources. Implementing the goals and aims of this project positions North Carolina A&T well for making significant contributions in eliminating health disparities. In addition, the university will be well positioned to create a Center of Excellence in Health Disparities Research and Training.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD000546-10
Application #
8296133
Study Section
Special Emphasis Panel (ZMD1-LW (10))
Program Officer
Hunter, Deloris
Project Start
2003-09-30
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2014-06-30
Support Year
10
Fiscal Year
2012
Total Cost
$782,221
Indirect Cost
$284,186
Name
North Carolina Agri & Tech State University
Department
Type
Other Domestic Higher Education
DUNS #
071576482
City
Greensboro
State
NC
Country
United States
Zip Code
27411
Mez, Jesse; Chung, Jaeyoon; Jun, Gyungah et al. (2017) Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement 13:119-129
Cukier, H N; Kunkle, B K; Hamilton, K L et al. (2017) Exome Sequencing of Extended Families with Alzheimer's Disease Identifies Novel Genes Implicated in Cell Immunity and Neuronal Function. J Alzheimers Dis Parkinsonism 7:
Hohman, Timothy J; Cooke-Bailey, Jessica N; Reitz, Christiane et al. (2016) Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimers Dement 12:233-43
Ghani, Mahdi; Reitz, Christiane; Cheng, Rong et al. (2015) Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol 72:1313-23
Lang, Rosalyn; Kelkar, Vinaya A; Byrd, Jennifer R et al. (2013) African American participation in health-related research studies: indicators for effective recruitment. J Public Health Manag Pract 19:110-8
Reitz, Christiane; Jun, Gyungah; Naj, Adam et al. (2013) Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans. JAMA 309:1483-92
Gordon, Ethel J; Kelkar, Vinaya (2009) Natural killer T cell facilitated engraftment of rat skin but not islet xenografts in mice. Xenotransplantation 16:135-44