Lipidomic and DNA microarray analyses of peripheral blood in African-American adults with type II diabetes Candidate: Jinghe Mao Career Development Plan: 1. Submit an AREA grant at the third year, MBRS at the fourth year and RO1 at the last yearofRIMI funding. 2. Foster junior faculty to establish projects related health disparities. 3. Continue to train more students in research and prepare them to go to graduate school and health professional school. 4. Develop new curricular plan to stimulate student learning.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD002725-04
Application #
8114158
Study Section
Special Emphasis Panel (ZMD1)
Project Start
Project End
Budget Start
2010-08-01
Budget End
2011-07-31
Support Year
4
Fiscal Year
2010
Total Cost
$124,298
Indirect Cost
Name
Tougaloo College
Department
Type
DUNS #
072618572
City
Tougaloo
State
MS
Country
United States
Zip Code
39174
Chakraborty, S; Asare, B K; Biswas, P K et al. (2016) Designer interface peptide grafts target estrogen receptor alpha dimerization. Biochem Biophys Res Commun 478:116-122
Asare, Bk; Rajnarayanan, Rv (2015) New Sites for Old Suspects: Environmental Allosteric Modifiers of Nuclear Hormone Receptors. J Pharmacol Clin Toxicol 3:
Sengupta, Bidisha; Reilly, Samantha M; Davis Jr, Donald E et al. (2015) Excited state proton transfer of natural flavonoids and their chromophores in duplex and tetraplex DNAs. J Phys Chem B 119:2546-56
Pahari, Biswapathik; Sengupta, Bidisha; Chakraborty, Sandipan et al. (2013) Contrasting binding of fisetin and daidzein in ?-cyclodextrin nanocavity. J Photochem Photobiol B 118:33-41
Zhao, Chen; Mao, Jinghe; Ai, Junmei et al. (2013) Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus. BMC Med Genomics 6 Suppl 1:S12
Hennington, Bettye Sue; Alexander, Barbara T (2013) Linking intrauterine growth restriction and blood pressure: insight into the human origins of cardiovascular disease. Circulation 128:2179-80
Chaudhuri, Sudip; Sengupta, Bidisha; Taylor, Jasmine et al. (2013) Interactions of dietary flavonoids with proteins: insights from fluorescence spectroscopy and other related biophysical studies. Curr Drug Metab 14:491-503
Chakraborty, Sandipan; Cole, Shawn; Rader, Nicholas et al. (2012) In silico design of peptidic inhibitors targeting estrogen receptor alpha dimer interface. Mol Divers 16:441-51
Chakraborty, Sandipan; Chaudhuri, Sudip; Pahari, Biswapathik et al. (2012) A CRITICAL STUDY ON THE INTERACTIONS OF HESPERITIN WITH HUMAN HEMOGLOBIN: FLUORESCENCE SPECTROSCOPIC AND MOLECULAR MODELING APPROACH. J Lumin 132:1522-1528
Sengupta, Bidisha; Chakraborty, Sandipan; Crawford, Maurice et al. (2012) Characterization of diadzein-hemoglobin binding using optical spectroscopy and molecular dynamics simulations. Int J Biol Macromol 51:250-8

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