It is postulated that one of the most effective strategies to ameliorate health disparities is to reduce tobacco exposure among African-American (AA) children and their parents. Exposure to the deleterious effects of involuntary secondhand smoking remains a major public health hazard;particularly for the most vulnerable in our society ~ children. Population-based surveys indicate that approximately 50% of children manifest exposure to secondhand smoke (SHS);and that AA children exhibit the highest rates of SHS exposure. The high rate of SHS exposure in children is particularly alarming because the life-course of smoking-related diseases such as asthma, hypertension, diabetes and cardiovascular disease have their onset during childhood. We anticipate that children living in the predominately low-income, AA partner community targeted by this MSM CEHD Program are particularly vulnerable to this toxin exposure. However, the causes and pathobiological consequences of SHS exposure in AA children remain poorly defined. This project will provide the first in-depth characterization of the social determinants and effects of SHS exposure on cardiovascular, metabolic and pulmonary health in AA children. These studies will provide new insights that will guide the development of more effective interventions to prevent tobacco exposure in AA families. Our approach utilizes a socio-ecological model of childhood SHS exposure that posits a multi-level interplay between the child's neighborhood characteristics, family context and individual biological factors. Our working hypothesis poses that certain elements in the 'built environment'predispose AA children to increased involuntary tobacco exposure (e.g. high density of tobacco marketing outlets;crowded housing conditions). Secondly, we hypothesize that parents determine childhood SHS exposure by: 1) parent risk behaviors (e.g. parent tobacco smoking), 2) parent health literacy and 3) parent psychosocial factors that influence childhood SHS exposure (perceived stress;social support). The project's specific aims are:
Aim 1 : Define the neighborhood characteristics, psychosocial factors and parenting behaviors associated with high secondhand smoke exposure in African-American children.
Aim 2 : Define the relationship between secondhand smoke exposure during childhood and vascular dysfunction, a pre-clinical marker of cardio-metabolic disease.
Aim 3 : Develop a predictive model to identify vulnerable children at high-risk for SHS exposure.
One of the most effective strategies to ameliorate health disparities is to reduce tobacco exposure among African-American (AA) children and their parents. Approximately 50% of children manifest exposure to second hand smoke (SHS);and AA children exhibit the highest rates of SHS exposure. This project will provide the first in-depth characterization of the social determinants and effects of SHS exposure on cardiovascular, metabolic and pulmonary health in AA children.
|Akintobi, Tabia Henry; Lockamy, Elise; Goodin, Lisa et al. (2018) Processes and Outcomes of a Community-Based Participatory Research-Driven Health Needs Assessment: A Tool for Moving Health Disparity Reporting to Evidence-Based Action. Prog Community Health Partnersh 12:139-147|
|Smith, Selina A; Ansa, Benjamin E; Yoo, Wonsuk et al. (2018) Determinants of adherence to physical activity guidelines among overweight and obese African American breast cancer survivors: implications for an intervention approach. Ethn Health 23:194-206|
|Twiner, Michael J; Marinica, Alexander L; Kuper, Kenneth et al. (2017) Screening and Treatment for Subclinical Hypertensive Heart Disease in Emergency Department Patients With Uncontrolled Blood Pressure: A Cost-effectiveness Analysis. Acad Emerg Med 24:168-176|
|Westney, Gloria; Foreman, Marilyn G; Xu, Junjun et al. (2017) Impact of Comorbidities Among Medicaid Enrollees With Chronic Obstructive Pulmonary Disease, United States, 2009. Prev Chronic Dis 14:E31|
|Adedinsewo, Demilade; Xu, Junjun; Agasthi, Pradyumna et al. (2017) Effect of Digoxin Use Among Medicaid Enrollees With Atrial Fibrillation. Circ Arrhythm Electrophysiol 10:e004573|
|Smith, Selina A; Claridy, Mechelle D; Whitehead, Mary S et al. (2016) Factors associated with body mass index among African American breast cancer survivors. J Ga Public Health Assoc 5:259-265|
|Ramirez, Lindsey A; Chung, Yunmi; Wonsuk, Yoo et al. (2016) Determinants of adherence to nutrition-related cancer prevention guidelines among African American breast cancer survivors. J Ga Public Health Assoc 6:210-222|
|Ansa, Benjamin E; White, Sashia; Chung, Yunmi et al. (2016) Trends in HIV Testing among Adults in Georgia: Analysis of the 2011-2015 BRFSS Data. Int J Environ Res Public Health 13:|
|Yan, Fengxia; Cha, EunSeok; Lee, Elisa T et al. (2016) A Self-assessment Tool for Screening Young Adults at Risk of Type 2 Diabetes Using Strong Heart Family Study Data. Diabetes Educ 42:607-17|
|Cooke, Tiffany; Bastien, Gilberte; Xu, Junjun et al. (2016) Major Depressive Disorder and Condom Use in Young Adult Females. HSOA J Psychiatry Depress Anxiety 2:|
Showing the most recent 10 out of 33 publications