The overall goal of the Rush Center of Excellence on Disparities in HIV and Aging (Rush CEDHA) is to provide an infrastructure to support collaborative, multidisciplinary epidemiologic research focused on understanding and eliminating racial disparities in the aging-related consequences of HIV. The Administrative Core will exercise overall scientific leadership of the Rush CEDHA in order to set the overall direction of the Center, ensure optimal utilization of Rush CEDHA resources, and serve as a resource for health disparities related activities at the national and local level. The responsibility for overall scientific leadership will rest with Dr. Barnes as CEDHA Director and is shared with and exercised through the Executive Committee composed of the two Associate Directors, the Core Leaders, the statistician and data manager, and an administrator, and members outside the CEDHA representing users ofthe Rush CEDHA resources. Three other committees will carry out specific functions to aid the proposed Center in achieving its goals. The Internal Advisory Board, composed of six representatives from the three partnering institutions - Rush University, John H. Stroger, Jr. Hospital of Cook County (Ruth M. Rothstein CORE Center), and University of Illinois at Chicago, will provide advice concerning the directions of Rush CEDHA efforts and sen/e as a mechanism for reaching consensus on major decisions. The External Advisory Board, composed of distinguished members from outside the institution with national prominence in research on health disparities, HIV, or aging will assess Rush CEDHA progress and provide advice concerning the direction CEDHA efforts should take. The Clinical Data and Biospecimen Distribution Committee will evaluate all requests for data, access to participants for research studies, and biospecimens from persons evaluated in the Research Core. Finally, the Administrator will manage Center finances to ensure the efficient use of Center resources.

Public Health Relevance

The Administrative Core will ensure that the rich resources generated by the Rush CEDHA will be widely disseminated to the research community to support studies that are essential to combatting the pervasive health disparities between older African Americans and whites infected with HIV, a large and growing public health challenge.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD006886-04
Application #
8804203
Study Section
Special Emphasis Panel (ZMD1)
Project Start
Project End
2016-01-31
Budget Start
2015-02-01
Budget End
2016-01-31
Support Year
4
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Rush University Medical Center
Department
Type
DUNS #
068610245
City
Chicago
State
IL
Country
United States
Zip Code
60612
Jansen, Willemijn J; Wilson, Robert S; Visser, Pieter Jelle et al. (2018) Age and the association of dementia-related pathology with trajectories of cognitive decline. Neurobiol Aging 61:138-145
Nguyen, Annie L; McNeil, Candice J; Han, S Duke et al. (2018) Risk and protective factors for health-related quality of life among persons aging with HIV. AIDS Care 30:518-522
Rodrigues, Jovita; Capuano, Ana W; Barnes, Lisa L et al. (2018) Effect of Antidepressant Medication Use and Social Engagement on the Level of Depressive Symptoms in Community-Dwelling, Older African Americans and Whites With Dementia. J Aging Health :898264318772983
Krueger, Kristin R; Adeyemi, Oluwatoyin; Leurgans, Sue et al. (2017) Association of cognitive activity and neurocognitive function in blacks and whites with HIV. AIDS 31:437-441
Han, S Duke; Adeyemi, Oluwatoyin; Wilson, Robert S et al. (2017) Loneliness in Older Black Adults with Human Immunodeficiency Virus Is Associated with Poorer Cognition. Gerontology 63:253-262
Turner, Arlener D; James, Bryan D; Capuano, Ana W et al. (2017) Perceived Stress and Cognitive Decline in Different Cognitive Domains in a Cohort of Older African Americans. Am J Geriatr Psychiatry 25:25-34
Arvanitakis, Zoe; Fleischman, Debra A; Arfanakis, Konstantinos et al. (2016) Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment. Brain Struct Funct 221:2135-46
Lim, Andrew S P; Fleischman, Debra A; Dawe, Robert J et al. (2016) Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults. Sleep 39:227-35
Arfanakis, Konstantinos; Wilson, Robert S; Barth, Christopher M et al. (2016) Cognitive activity, cognitive function, and brain diffusion characteristics in old age. Brain Imaging Behav 10:455-63
Fleischman, Debra A; Yang, Jingyun; Arfanakis, Konstantinos et al. (2015) Physical activity, motor function, and white matter hyperintensity burden in healthy older adults. Neurology 84:1294-300

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