The P20 award by the NCMHD to LLU in 2005 was instrumental for establishing the first and only COE on health disparifies research in the Inland Empire of Southern California. The mission of this center is to reduce or eliminate health disparities in the local communifies and nafionally through a robust biomedical Research Core focused on diabetes and cancer that is interconnected with a comprehensive Research Training and Education Core, and a dynamic and successful Community Outreach and Engagement Core. The CHDMM serves a vast geographical area with a populafion of over 3.5 million. It is esfimated that by 2015, over 55% of the population in this region will belong to ethnic groups (i.e. Hispanics and African American) that traditionally have a low socioeconomic status and disadvantaged background (LSESDB). The California County Health Status Profiles 2011 ranked this region pooriy in health, and in agerelated deaths due to diabetes and cancer (2). The CHDMM is now poised for continuing expanding its sustainability and growth. The Center is currentiy comprised of 14 principal investigators with faculty appointments at the LLU Schools of Medicine and Public Health. Seven of these investigators are physically housed in contiguous laboratories within the CHDMM, focusing their research programs on biological and translational aspects of diabetes and cancer. In addition, a number of faculty members in the basic science departments ofthe School of Medicine hold adjunct member appointments in the CHDMM and contribute with their expertise in areas that complement the research mission of this center. A weekly """"""""chalk talk style"""""""" informal research seminar brings together these investigators and provides a forum where original, unpublished data are discussed. CHDMM researchers interact on a regular basis to address biological aspects underiying health disparities, design translational initiatives, and create and expand programs for community education and participafion. The LLU CHDMM Annual Health Disparities Symposium also showcases research progress and brings together the biomedical research community, research trainees, university administrators, community leaders, and national leaders in health disparities. These interactions create a highly dynamic and collegial environment for collaborative research, training the next generation of health disparities researchers, and focusing community engagement.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Exploratory Grants (P20)
Project #
Application #
Study Section
Special Emphasis Panel (ZMD1-RN)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Loma Linda University
Loma Linda
United States
Zip Code
Arthur, Kristen N; Spencer-Hwang, Rhonda; Knutsen, Synnøve F et al. (2018) Are perceptions of community safety associated with respiratory illness among a low-income, minority adult population? BMC Public Health 18:1089
Cajigas-Du Ross, Christina K; Martinez, Shannalee R; Woods-Burnham, Leanne et al. (2018) RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance. Oncotarget 9:30363-30384
Rowland, Leah K; Campbell, Petreena S; Mavingire, Nicole et al. (2018) Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand-mediated triple negative breast cancer cell death. J Cell Biochem :
Woods-Burnham, Leanne; Cajigas-Du Ross, Christina K; Love, Arthur et al. (2018) Glucocorticoids Induce Stress Oncoproteins Associated with Therapy-Resistance in African American and European American Prostate Cancer Cells. Sci Rep 8:15063
Woods-Burnham, Leanne; Stiel, Laura; Wilson, Colwick et al. (2018) Physician Consultations, Prostate Cancer Knowledge, and PSA Screening of African American Men in the Era of Shared Decision-Making. Am J Mens Health 12:751-759
Campbell, Petreena S; Mavingire, Nicole; Khan, Salma et al. (2018) AhR ligand aminoflavone suppresses ?6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells. J Cell Physiol 234:108-121
Cordero, Kathia; Coronel, Gemma G; Serrano-Illán, Miguel et al. (2018) Effects of Dietary Vitamin E Supplementation in Bladder Function and Spasticity during Spinal Cord Injury. Brain Sci 8:
Greer-Phillips, Suzanne E; Sukomon, Nattakan; Chua, Teck Khiang et al. (2018) THE AER2 RECEPTOR FROM VIBRIO CHOLERAE IS A DUAL PAS-HEME OXYGEN SENSOR. Mol Microbiol :
Gonda, Amber; Kabagwira, Janviere; Senthil, Girish N et al. (2018) Exosomal survivin facilitates vesicle internalization. Oncotarget 9:34919-34934
Lewis, Charlotte M; Gamboa-Maldonado, Thelma; Carlos Belliard, Juan et al. (2018) Patient and Community Health Worker Perceptions of Community Health Worker Clinical Integration. J Community Health :

Showing the most recent 10 out of 106 publications