Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Exploratory Grants (P20)
Project #
1P20NS030324-01
Application #
3861699
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Vermont & St Agric College
Department
Type
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Shackford, S R; Bourguignon, P R; Wald, S L et al. (1998) Hypertonic saline resuscitation of patients with head injury: a prospective, randomized clinical trial. J Trauma 44:50-8
Shackford, S R (1997) Effect of small-volume resuscitation on intracranial pressure and related cerebral variables. J Trauma 42:S48-53
Chappell, J E; Shackford, S R; McBride, W J (1997) Effect of hemodilution with diaspirin cross-linked hemoglobin on intracranial pressure, cerebral perfusion pressure, and fluid requirements after head injury and shock. J Neurosurg 86:131-8
Gourin, C G; Shackford, S R (1997) Production of tumor necrosis factor-alpha and interleukin-1beta by human cerebral microvascular endothelium after percussive trauma. J Trauma 42:1101-7
Shatos, M A; Doherty, J M; Penar, P L et al. (1996) Suppression of plasminogen activator inhibitor-1 release from human cerebral endothelium by plasminogen activators. A factor potentially predisposing to intracranial bleeding. Circulation 94:636-42
Chappell, J E; McBride, W J; Shackford, S R (1996) Diaspirin cross-linked hemoglobin resuscitation improves cerebral perfusion after head injury and shock. J Trauma 41:781-8
Luh, E H; Shackford, S R; Shatos, M A et al. (1996) The effects of hyperosmolarity on the viability and function of endothelial cells. J Surg Res 60:122-8
Gourin, C G; Shackford, S R (1996) Influence of percussion trauma on expression of intercellular adhesion molecule-1 (ICAM-1) by human cerebral microvascular endothelium. J Trauma 41:129-35
Schmoker, J D; Shackford, S R; Zhuang, J (1996) The effect of lesion volume on cerebral vasomotor tone after focal brain injury and shock. J Neurotrauma 13:67-78
Zhuang, J; Shackford, S R; Schmoker, J D et al. (1995) Colloid infusion after brain injury: effect on intracranial pressure, cerebral blood flow, and oxygen delivery. Crit Care Med 23:140-8

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