EXCEED THE SPACEPROVIDED.This renewal application for the Research Centers in Minority Institutions Clinical Research infrastructure(RCRII) at Morehouse School of Medicine is submitted in responseto NOT-RR-05-001. The MorehouseSchool of Medicine (MSM) RCRII program seeks to augment and strengthen the clinical research capacity atMorehouse School of Medicine by 1) providing an infrastructure to conduct state-of-the art clinical andtranslational research on diseases that disproportionately effect AfricanAmericans, and other ethnicminorities; 2) focused training andfaculty development programs to increase the number of clinicianscientists qualified to serve as principal investigators; 3) facilitate basic science and clinical sciencecollaborations as a mechanism to foster research translation. Long range, we anticipate that the RCRII atMorehouse School of Medicine will develop sufficient clinical research capacity in order to compete for non-RCMI support of the Clinical Research Center. Ultimately, we envision that MSMwill be a leading institutionon clinical and translational research that will improve the health of the nation's ethnic minority citizens byreducing and eliminating health care disparities. The current funding cycle (00-04) has shown a remarkableand unprecedented growth in MSM's clinical research program. Despite these successes, the MSM ClinicalResearch Program is still early in its development and faces significant challenges, including small numbersof independently funded clinical research investigators. This application will therefore build on our initialsuccess by 1)expanding and strengthening the core clinical research infrastructure; 2) increasing the cadreof investigators who will pursue hypothesis driven, and other independent research applications. Wepropose to 1) establish a new nutrition core, 2) consolidate the analytical lab under the Analytical and ProteinProfiling Core, 3) develop the informatics core to support a CRC based data warehouse and clinical trial datarepository, and 4) promote an integrated approach to faculty development around the MSCRprogram.
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