The goal of the RCRII Program at the Medical Sciences Campus is to develop the necessary infrastructure and support services to conduct clinical research activities and to stimulate the clinical research potential of our faculty. The following specific aims have been identified: a) to create a self-supported infrastructure for clinical research including appropriate physical facilities, as well as administrative and research support services; b) to enhance the research potential of current and new clinical research faculty and to encourage collaborative research between clinical and basic investigators; c) to target research programs or areas for development. To achieve these objectives, we propose to create three major divisions: The Division of Clinical Research Support Services will provide the necessary administrative and technical personnel, shared equipment and support services to facilitate the conduct of clinical research. These support services will be located within a 15,000 sq. ft. physical facility that has been identified within the University Hospital. The area will include examination and infusion rooms, research nurse stations, administrative offices, a pharmacy, a core laboratory, a biostatistical unit, etc. The Division of Clinical Research Faculty Development will focus on identifying mechanisms for stimulating the participation of faculty and medical students in clinical research through activities such as seminars, off-campus research experiences, exchange with consultants and mentors, training programs and collaboration with basic scientists. Faculty advisors will be identified among researchers on campus, as well as established GCRC programs, to advise new investigators on training programs, technical and research problems, grant applications, etc. The Division of clinical Research Development will be constituted by the pilot projects targeted for clinical research development. Five pilot projects have been selected by the CRAC as potential focus areas for support. These projects will receive support for 1-2 years, unless evaluation of their progress by the CRAC leads to a recommendation for extension. The program will attempt to develop the research potential of these investigators by providing the necessary instrumentation and technical support and by facilitating the development of new approaches to their research which have been untried or undeveloped due to lack of equipment and/or expertise. It is expected that this support will allow the investigators to compete successfully for external funding.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR011126-04
Application #
2772032
Study Section
Special Emphasis Panel (SRC (01))
Project Start
1995-09-30
Project End
2000-08-31
Budget Start
1998-09-01
Budget End
1999-08-31
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Type
Organized Research Units
DUNS #
City
San Juan
State
PR
Country
United States
Zip Code
00936
Cantres-Rosario, Yisel M; Acevedo-Mariani, Frances M; Pérez-Laspiur, Juliana et al. (2017) Microwave & magnetic proteomics of macrophages from patients with HIV-associated cognitive impairment. PLoS One 12:e0181779
Colon, Krystal; Perez-Laspiur, Juliana; Quiles, Raymond et al. (2016) Macrophage secretome from women with HIV-associated neurocognitive disorders. Proteomics Clin Appl 10:136-43
Vázquez-Santiago, Fabián J; Rivera-Amill, Vanessa (2015) Envelope gene evolution and HIV-1 neuropathogenesis. J Neuroinfect Dis 6:
Vázquez-Santiago, Fabián; García, Yashira; Rivera-Román, Ivelisse et al. (2015) Longitudinal Analysis of Cerebrospinal Fluid and Plasma HIV-1 Envelope Sequences Isolated From a Single Donor with HIV Asymptomatic Neurocognitive Impairment. J Virol Antivir Res 4:
Ríos, Grissel; Estrada, Marcos; Mayor, Angel M et al. (2014) Factors associated with tender point count in Puerto Ricans with fibromyalgia syndrome. P R Health Sci J 33:112-6
Gandhi, Rajesh T; Bosch, Ronald J; Aga, Evgenia et al. (2013) Residual plasma viraemia and infectious HIV-1 recovery from resting memory CD4 cells in patients on antiretroviral therapy: results from ACTG A5173. Antivir Ther 18:607-13
González, Lorena; Magno, Priscilla; Ortiz, Ana P et al. (2013) Esophageal cancer incidence rates by histological type and overall: Puerto Rico versus the United States Surveillance, Epidemiology, and End Results population, 1992-2005. Cancer Epidemiol 37:5-10
Murthy, Vijaya; Willis, Rohan; Romay-Penabad, Zurina et al. (2013) Value of isolated IgA anti-?2 -glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome. Arthritis Rheum 65:3186-93
Suárez, Erick; González, Lorena; Díaz-Toro, Elba C et al. (2013) Incidence of oral cavity and pharyngeal cancers by anatomical sites in population-based registries in Puerto Rico and the United States of America. P R Health Sci J 32:175-81
Ortiz, Ana Patricia; Romaguera, Josefina; Pérez, Cynthia M et al. (2013) Human papillomavirus infection in women in Puerto Rico: agreement between physician-collected and self-collected anogenital specimens. J Low Genit Tract Dis 17:210-7

Showing the most recent 10 out of 189 publications