Continuing support for the Clinical Research Center of the Medical Sciences Campus (MSC) is requested through the Research Centers for Minority Institutions Clinical Research Infrastructure Initiative (RCRII) Program. The goal of the RCRII Program at the MSC for the next five years is to continue developing the infrastructure and support services to facilitate clinical research activities and stimulate the research potential of the clinical faculty. The following specific aims have been identified: a) enhance the clinical faculty skills in modern principles and practices of clinical research, methodology of study design and statistical methods. b) intensify the specific research activity in the areas of diabetes, neurosciences, AIDS and establish a Neonatal Twin Registry to allow the study of metabolic and hereditary conditions in prospective studies, c) encourage collaborative projects between basic and clinical investigators as well as with other major research centers and Universities, and 2) increase the number of investigator initiated research with independent funding in order to assemble a critical mass of clinical investigators suitable for the progression of the RCRII to a General Clinical Research Center (GCRC). Three divisions already in operation will be entrusted with the task of accomplishing these objectives. The Clinical Research Faculty Development division will again focus on identifying the mechanism for stimulation the participation of the clinical faculty and students in clinical research through activities such as seminars, courses, training programs, exchange with consultants and mentors and the collaboration between basic and clinical researchers. This division will coordinate the """"""""Introduction to the Principles and Practice of Clinical Research"""""""", an NIH Services division will continue to provide the administrative and technical personnel, shared equipment, core laboratory and support services needed to facilitate the task of clinical research. This Division will also provide patient coordination services and biostatistical support. The Clinical Research Development division will be constituted by the pilot projects targeted for clinical research development with attention to the specific areas of diabetes, AIDS, neurosciences and the expansion of a neonatal Twin Registry in collaboration with Virginia Commonwealth University. These projects will be funded for 1-2 years allowing the investigators to compete for external funding and subsequently advance the obtainment of a GCRC.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
2P20RR011126-06
Application #
6190930
Study Section
Special Emphasis Panel (ZRR1-RCMI-5 (01))
Program Officer
Angus, C William
Project Start
1995-09-30
Project End
2005-08-31
Budget Start
2000-09-30
Budget End
2001-08-31
Support Year
6
Fiscal Year
2000
Total Cost
$759,802
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Type
Schools of Medicine
DUNS #
City
San Juan
State
PR
Country
United States
Zip Code
00936
Cantres-Rosario, Yisel M; Acevedo-Mariani, Frances M; Pérez-Laspiur, Juliana et al. (2017) Microwave & magnetic proteomics of macrophages from patients with HIV-associated cognitive impairment. PLoS One 12:e0181779
Colon, Krystal; Perez-Laspiur, Juliana; Quiles, Raymond et al. (2016) Macrophage secretome from women with HIV-associated neurocognitive disorders. Proteomics Clin Appl 10:136-43
Vázquez-Santiago, Fabián J; Rivera-Amill, Vanessa (2015) Envelope gene evolution and HIV-1 neuropathogenesis. J Neuroinfect Dis 6:
Vázquez-Santiago, Fabián; García, Yashira; Rivera-Román, Ivelisse et al. (2015) Longitudinal Analysis of Cerebrospinal Fluid and Plasma HIV-1 Envelope Sequences Isolated From a Single Donor with HIV Asymptomatic Neurocognitive Impairment. J Virol Antivir Res 4:
Ríos, Grissel; Estrada, Marcos; Mayor, Angel M et al. (2014) Factors associated with tender point count in Puerto Ricans with fibromyalgia syndrome. P R Health Sci J 33:112-6
Gandhi, Rajesh T; Bosch, Ronald J; Aga, Evgenia et al. (2013) Residual plasma viraemia and infectious HIV-1 recovery from resting memory CD4 cells in patients on antiretroviral therapy: results from ACTG A5173. Antivir Ther 18:607-13
González, Lorena; Magno, Priscilla; Ortiz, Ana P et al. (2013) Esophageal cancer incidence rates by histological type and overall: Puerto Rico versus the United States Surveillance, Epidemiology, and End Results population, 1992-2005. Cancer Epidemiol 37:5-10
Murthy, Vijaya; Willis, Rohan; Romay-Penabad, Zurina et al. (2013) Value of isolated IgA anti-?2 -glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome. Arthritis Rheum 65:3186-93
Suárez, Erick; González, Lorena; Díaz-Toro, Elba C et al. (2013) Incidence of oral cavity and pharyngeal cancers by anatomical sites in population-based registries in Puerto Rico and the United States of America. P R Health Sci J 32:175-81
Ortiz, Ana Patricia; Romaguera, Josefina; Pérez, Cynthia M et al. (2013) Human papillomavirus infection in women in Puerto Rico: agreement between physician-collected and self-collected anogenital specimens. J Low Genit Tract Dis 17:210-7

Showing the most recent 10 out of 189 publications