The general aim of this project is to determine the oral health status and oral treatment needs of the sixty years and older population living in retirement housing for the elderly (egidas) in the city of San Juan, Puerto Rico and its association with behavioral factors, self reported systemic conditions, as well as saliva flow rate and composition. An overall oral health assessment has not been conducted in Puerto Rico in the last four decades. The proportion of elderly people in the city of San Juan , as well as, Puerto Rico and the U.S. has risen significantly over the last ten years and is expected to continue to do so. From 1980-1990 an increase of 20.4% was observed in San Juan for this age group and is estimated to represent 20.6% of the population of the city in 1997. The proposed investigation is a cross-sectional epidemiological study in which a comprehensive array of oral health indicators and associated variables will be assessed in 200 subjects from """"""""egidas"""""""". A sample of 200 eligible residents will be obtained by cluster sampling. Clinical data will be obtained from comprehensive oral exams. Detailed demographic, behavioral, oral knowledge, attitudes, and utilization of dental services data will be collected. In addition, parotid saliva will be collected and analyzed for secretory IgA and IgAI concentrations and for concentrations of fluoride and other ions (calcium, phosphate, magnesium, sodium). Data gathered will be analyzed in order to: (1) characterize the oral health status and treatment needs of this population and (2) explore the interrelationships between a variety of putative explanatory factors and the prevalence of coronal and root caries and periodontal disease (3) assess the relationship between salivary flow rate, composition, and SigA and SIgA1 concentrations with oral health status, systematic conditions and use of medications in this group.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR011126-08
Application #
6652318
Study Section
Special Emphasis Panel (ZRR1)
Project Start
2002-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
8
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Type
DUNS #
City
San Juan
State
PR
Country
United States
Zip Code
00936
Cantres-Rosario, Yisel M; Acevedo-Mariani, Frances M; Pérez-Laspiur, Juliana et al. (2017) Microwave & magnetic proteomics of macrophages from patients with HIV-associated cognitive impairment. PLoS One 12:e0181779
Colon, Krystal; Perez-Laspiur, Juliana; Quiles, Raymond et al. (2016) Macrophage secretome from women with HIV-associated neurocognitive disorders. Proteomics Clin Appl 10:136-43
Vázquez-Santiago, Fabián J; Rivera-Amill, Vanessa (2015) Envelope gene evolution and HIV-1 neuropathogenesis. J Neuroinfect Dis 6:
Vázquez-Santiago, Fabián; García, Yashira; Rivera-Román, Ivelisse et al. (2015) Longitudinal Analysis of Cerebrospinal Fluid and Plasma HIV-1 Envelope Sequences Isolated From a Single Donor with HIV Asymptomatic Neurocognitive Impairment. J Virol Antivir Res 4:
Ríos, Grissel; Estrada, Marcos; Mayor, Angel M et al. (2014) Factors associated with tender point count in Puerto Ricans with fibromyalgia syndrome. P R Health Sci J 33:112-6
Murthy, Vijaya; Willis, Rohan; Romay-Penabad, Zurina et al. (2013) Value of isolated IgA anti-?2 -glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome. Arthritis Rheum 65:3186-93
Suárez, Erick; González, Lorena; Díaz-Toro, Elba C et al. (2013) Incidence of oral cavity and pharyngeal cancers by anatomical sites in population-based registries in Puerto Rico and the United States of America. P R Health Sci J 32:175-81
Ortiz, Ana Patricia; Romaguera, Josefina; Pérez, Cynthia M et al. (2013) Human papillomavirus infection in women in Puerto Rico: agreement between physician-collected and self-collected anogenital specimens. J Low Genit Tract Dis 17:210-7
Cantres-Rosario, Yisel; Plaud-Valentín, Marines; Gerena, Yamil et al. (2013) Cathepsin B and cystatin B in HIV-seropositive women are associated with infection and HIV-1-associated neurocognitive disorders. AIDS 27:347-56
Agsalda-Garcia, Melissa; Shiramizu, Bruce; Melendez, Loyda et al. (2013) Different levels of HIV DNA copy numbers in cerebrospinal fluid cellular subsets. J Health Care Poor Underserved 24:8-16

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