This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Drew/UCLA Export Center builds upon a long tradition of collaboration between Drew and UCLA, close involvement wit the minority communities, substantial success in training minority investigators in disparities research, and a distinguished record of scholarship in the area of disparities. The Center will address health disparities in the larges and one of the most diverse counties in the United States. The Center will emphasize diabetes mellitus and mental health and illness in Latinos and African Americans in its initial years, but eventually will address disparities in other conditions and, possibly, other ethnic/racial groups. The center is organized into seven cores: (1) an Administrative, Planning and Evaluation Core, which will be direct the Center, select Center participants, supervise evaluation of all Center activities, select pilot projects, coordinate relationships to the External Advisory Board and Community Advisory Board and management of budgets and reports; (2) a training and Mentorship Core, which will recruit and mentor minority junior investigators in the areas of disparities and mental health, providing them with individualized curricula, career guidance and superivision; (3) a Community Outreach/Information Dissemination Core, which will disseminate culturally-sensitivie health information to low-income Latinos and African Americans and evidenced-based helath care information to their providers, parther with communities to engage community members in research, and provide mentorship to junior faculty in comjmunity-based research activities; (4) a Research Core that will translate an intervention of proved efficacy for lowering the incidence of diabetes mellitus through weight loss into a form that will be acceptable to and useful in low-income minority populations (initially Latinos);(5 and 6) two Shared Resources Cores, that will bring state-of-the-art instruments, study designs and analytical methods to the research activities of Center investigators; and (7) a Pilot Projects Core that will fund pilot projects inthe area of disparities for Center Investigators, giving highest priority to the substantial number of promising junior investigators in the Center and it sponsoring institutions. The Center has established milestones for evaluation to assure that the Center''''s resources are optimally applied to addressing the major problems facing the nation in the area of disparities in health and health care.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR011145-12
Application #
7381045
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-09-01
Project End
2007-08-31
Budget Start
2006-09-01
Budget End
2007-08-31
Support Year
12
Fiscal Year
2006
Total Cost
$19,710
Indirect Cost
Name
Charles R. Drew University of Medicine & Science
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059
Juraschek, Stephen P; Miller 3rd, Edgar R; Appel, Lawrence J (2018) Orthostatic Hypotension and Symptoms in the AASK Trial. Am J Hypertens 31:665-671
Grams, Morgan E; Sang, Yingying; Ballew, Shoshana H et al. (2018) Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate. Kidney Int 93:1442-1451
Inker, Lesley A; Grams, Morgan E; Levey, Andrew S et al. (2018) Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium. Am J Kidney Dis :
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Juraschek, Stephen P; Appel, Lawrence J; Miller 3rd, Edgar R (2017) Metoprolol Increases Uric Acid and Risk of Gout in African Americans With Chronic Kidney Disease Attributed to Hypertension. Am J Hypertens 30:871-875
Chen, Teresa K; Tin, Adrienne; Peralta, Carmen A et al. (2017) APOL1 Risk Variants, Incident Proteinuria, and Subsequent eGFR Decline in Blacks with Hypertension-Attributed CKD. Clin J Am Soc Nephrol 12:1771-1777
Liang, Su; Bian, Xiaomei; Liang, Dong et al. (2016) Solution formulation development and efficacy of MJC13 in a preclinical model of castration-resistant prostate cancer. Pharm Dev Technol 21:121-6
Chen, Teresa K; Choi, Michael J; Kao, W H Linda et al. (2015) Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression. Clin J Am Soc Nephrol 10:2128-35
Chen, Teresa K; Estrella, Michelle M; Astor, Brad C et al. (2015) Longitudinal changes in hematocrit in hypertensive chronic kidney disease: results from the African-American Study of Kidney Disease and Hypertension (AASK). Nephrol Dial Transplant 30:1329-35
Chang, Alex; Greene, Tom H; Wang, Xuelei et al. (2015) The effects of weight change on glomerular filtration rate. Nephrol Dial Transplant 30:1870-7

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