This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Healthy People 2010 recognizes chronic kidney disease (CKD) as one of 28 focus areas to improve the nation?s health. To address these goals, Charles R. Drew University of Medicine and Science (Drew) is proposing to establish a Comprehensive Center on Health Disparities (CCHD) focusing on CKD. The foundation for the center will be a formalized partnership between Drew, UCLA and RAND. The Drew/RAND/UCLA CCHD-CKD will bring important strengths to disparities-focused research. Los Angeles County is an ideal setting for this center, being one of the most diverse counties in the United States, and one with major population concentrations of disadvantaged minority groups disproportionately affected by high rates of CKD (and major CKD risk factors), related morbidity and mortality, as well as some of the lowest rates of educational attainment, income and health insurance coverage in the nation. The center will focus on contextual, community, and health care delivery factors as they relate to CKD disparities among the nation?s minority and disadvantaged populations, using a bench to bedside approach that impacts relevant health care policy. The overall goals are to reduce the incidence of death related to CKD and improve the quality of life for those who have CKD. Drew and its partners propose to address these goals through the activities of four cores: 1) The Administrative and Scientific Core, 2) the Community Outreach and Information Dissemination (Community) Core, 3) the Chronic Kidney Disease Health Outcomes and Policy Core, and 4) the Developmental Core.
The Specific Aims of the Drew/RAND/UCLA CCHD-CKD are to: 1) Promote the conduct of methodologically rigorous research (focusing on national CKD priority areas) aimed at improving outcomes for CKD patients; 2) Promote the conduct of methodologically rigorous research (focusing on national CKD priority areas) aimed at reducing disparities in CKD and CKD risk factors for disadvantaged African American and Latino patients; 3) Build research capacity and provide both formal training in academic and community-based settings for CKD/health disparities researchers at Drew University; 4) Educate and increase the participation of medically underserved minorities in evidence-based health promotion and disease prevention research directed toward CKD and CKD risk factors; and 5) Disseminate results of relevant efficacy studies and health information in a culturally and linguistically appropriate manner to this population, community-based health care providers, the broader academic community, and to health policy makers.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR011145-12
Application #
7381046
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-09-01
Project End
2007-08-31
Budget Start
2006-09-01
Budget End
2007-08-31
Support Year
12
Fiscal Year
2006
Total Cost
$39,421
Indirect Cost
Name
Charles R. Drew University of Medicine & Science
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059
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Inker, Lesley A; Grams, Morgan E; Levey, Andrew S et al. (2018) Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium. Am J Kidney Dis :
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Chen, Teresa K; Choi, Michael J; Kao, W H Linda et al. (2015) Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression. Clin J Am Soc Nephrol 10:2128-35
Chen, Teresa K; Estrella, Michelle M; Astor, Brad C et al. (2015) Longitudinal changes in hematocrit in hypertensive chronic kidney disease: results from the African-American Study of Kidney Disease and Hypertension (AASK). Nephrol Dial Transplant 30:1329-35
Chang, Alex; Greene, Tom H; Wang, Xuelei et al. (2015) The effects of weight change on glomerular filtration rate. Nephrol Dial Transplant 30:1870-7

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