There are seven and half faculty positions in the Department and two faculty have biomedical research projects. Both of these projects are using molecular biology techniques to study the natural resistance of warm-blooded animals to snake venom. The biomedical faculty have published in professional refereed journals and have been extremely active in writing research grants. TAMUK needs an institutional infrastructure that will promote biomedical research through collaborative research linkages with other universities. The overall goal of the NIH/RIMI program is to expand biomedical research at the University by improving the research infrastructure. The objectives of the Infrastructure Project are to: (1) hire additional faculty with a biomedical research interest who will establish collaborative research with other universities, (2) use the Advisory Committee to insure that research links will be made with other universities, (3) develop a core research facility with technical support to operate the maintain the equipment, and (4) improve the Internet capabilities in the department and use it as a means of communicating with other investigators at collaborating universities. Three new faculty positions will be added to enhance the biomedical expertise of the University. Two of the positions will be in Biology (cell biologist, and geneticist) and one in Chemistry (biochemist). The new faculty will have a 6 hr teaching load, seed money for research, laboratory space, and graduate student support for research (this will be provided by the University). A core research facility with instruments, computers, telecommunication equipment, and technical support will be established. The computer and telecommunication facility will be essential to enhance collaborative research between participating universities. Faculty and students from different universities will be able to communicate through the Internet. The World Wide Web can be used to establish joint home pages for collaborative research projects. Joint seminars, research meetings, and student defenses can take place through a telecommunication system. The core research facility will contain large expensive equipment that can be used by all faculty for research projects. The facility will have a full time research associate to operate and maintain the equipment. The Core Research Facility will have six faculty users for research projects and will stimulate collaborative research projects with participating universities. The facility will be essential in attracting quality research faculty. The students will obtain training and research experience that will allow them to make the transition into a Ph.D. at major universities.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR011594-05
Application #
6206494
Study Section
Project Start
1999-09-30
Project End
2000-09-29
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
5
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Texas A&M University-Kingsville
Department
Type
DUNS #
City
Kingsville
State
TX
Country
United States
Zip Code
78363
Salazar, Ana Maria; Guerrero, Belsy; Cantu, Bruno et al. (2009) Venom variation in hemostasis of the southern Pacific rattlesnake (Crotalus oreganus helleri): isolation of hellerase. Comp Biochem Physiol C Toxicol Pharmacol 149:307-16
Galan, Jacob A; Sanchez, Elda E; Rodriguez-Acosta, Alexis et al. (2004) Neutralization of venoms from two Southern Pacific Rattlesnakes (Crotalus helleri) with commercial antivenoms and endothermic animal sera. Toxicon 43:791-9
Sanchez, Elda E; Ramirez, Maria Susana; Galan, Jacob A et al. (2003) Cross reactivity of three antivenoms against North American snake venoms. Toxicon 41:315-20
Sanchez, Elda E; Galan, Jacob A; Perez, John C et al. (2003) The efficacy of two antivenoms against the venom of North American snakes. Toxicon 41:357-65
McKeller, Morgan R; Perez, John C (2002) The effects of Western Diamondback Rattlesnake (Crotalus atrox) venom on the production of antihemorrhagins and/or antibodies in the Virginia opossum (Didelphis virginiana). Toxicon 40:427-39
Perez, J C; McKeller, M R; Perez, J C et al. (2001) An internet database of crotaline venom found in the United States. Toxicon 39:621-32
Sanchez, E E; Soliz, L A; Ramirez, M S et al. (2001) Partial characterization of a basic protein from Crotalus molossus molossus (northern blacktail rattlesnake) venom and production of a monoclonal antibody. Toxicon 39:523-37
Martinez, R R; Perez, J C; Sanchez, E E et al. (1999) The antihemorrhagic factor of the Mexican ground squirrel, (Spermophilus mexicanus). Toxicon 37:949-54
Ramirez, M S; Sanchez, E E; Garcia-Prieto, C et al. (1999) Screening for fibrinolytic activity in eight Viperid venoms. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 124:91-8
Perez, J C; Sanchez, E E (1999) Natural protease inhibitors to hemorrhagins in snake venoms and their potential use in medicine. Toxicon 37:703-28

Showing the most recent 10 out of 11 publications