This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The function of this core is to support the scientific goals of this proposal by providing an administrative struc-ture for the coordination of the activities of the Principal Investigator, Project Leaders, and Core Directors. These functions include: administrative support of the Principal Investigator, administrative support for cores B, C and D, collection of financial records from Project Leaders, maintaining financial records of the individ-ual cores, preparing an annual financial report for the entire center, and coordination activities of the External Advisory Committee. Other activities may include coordinating faculty searches, workshops, and seminars.The senior mentors are also part of this core and are listed as co-investigators. The mentor-mentee assignments are as follows:Junior Investigator MentorR. Freiman K. BoekelheideM. Kim J. WandsA. Salomon D. MierkeJ. Singer W. AtwoodA. Zhitkovich A. KaneJ. Klysik J. SedivyW. Thompson C. LawrenceJ. Klysik J. SedivyW. Thompson C. Lawrence

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR015578-08
Application #
7609780
Study Section
Special Emphasis Panel (ZRR1-RI-8 (01))
Project Start
2007-05-01
Project End
2008-02-29
Budget Start
2007-05-01
Budget End
2008-02-29
Support Year
8
Fiscal Year
2007
Total Cost
$370,676
Indirect Cost
Name
Brown University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
001785542
City
Providence
State
RI
Country
United States
Zip Code
02912
Lovasco, Lindsay A; Gustafson, Eric A; Seymour, Kimberly A et al. (2015) TAF4b is required for mouse spermatogonial stem cell development. Stem Cells 33:1267-76
Ribeiro, Jennifer R; Freiman, Richard N (2014) Estrogen signaling crosstalk: Implications for endocrine resistance in ovarian cancer. J Steroid Biochem Mol Biol 143:160-73
Casella, Cinzia; Miller, Daniel H; Lynch, Kerry et al. (2014) Oxysterols synergize with statins by inhibiting SREBP-2 in ovarian cancer cells. Gynecol Oncol 135:333-41
Grive, Kathryn J; Seymour, Kimberly A; Mehta, Rajvi et al. (2014) TAF4b promotes mouse primordial follicle assembly and oocyte survival. Dev Biol 392:42-51
Tomimaru, Yoshito; Xu, Chelsea Q; Nambotin, Sarah B et al. (2013) Loss of exon 4 in a human T-cell factor-4 isoform promotes hepatic tumourigenicity. Liver Int 33:1536-48
Minhas, Hassan M; Pescosolido, Matthew F; Schwede, Matthew et al. (2013) An unbalanced translocation involving loss of 10q26.2 and gain of 11q25 in a pedigree with autism spectrum disorder and cerebellar juvenile pilocytic astrocytoma. Am J Med Genet A 161A:787-91
De Cecco, Marco; Criscione, Steven W; Peckham, Edward J et al. (2013) Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements. Aging Cell 12:247-56
Li, Hua; Jogl, Gerwald (2013) Crystal structure of decaprenylphosphoryl-?- D-ribose 2'-epimerase from Mycobacterium smegmatis. Proteins 81:538-43
Tomimaru, Yoshito; Koga, Hironori; Yano, Hirohisa et al. (2013) Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma. Liver Int 33:1100-12
Tomimaru, Yoshito; Koga, Hironori; Shin, Tai Ho et al. (2013) The SxxSS motif of T-cell factor-4 isoforms modulates Wnt/?-catenin signal activation in hepatocellular carcinoma cells. Cancer Lett 336:359-69

Showing the most recent 10 out of 152 publications