This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator.
The aims of this pilot project are to establish a model system for monitoring neurite outgrowth in crustaceans and to study the influence of melatonin at the cellular and molecular levels on this process. Melatonin affects neurite growth and function in regions of the vertebrate brain, though the mechanisms are not yet known. Crustaceans provide robust and analogous systems for a variety of biomedical studies. In the first year of the project, we identified cell types that could be cultured to provide an assay for neurite growth. These cells came from the x-organ, a neurosecretory structure in the crustacean eyestalk.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016463-06
Application #
7381441
Study Section
Special Emphasis Panel (ZRR1-RI-7 (01))
Project Start
2006-05-01
Project End
2007-04-30
Budget Start
2006-05-01
Budget End
2007-04-30
Support Year
6
Fiscal Year
2006
Total Cost
$29,844
Indirect Cost
Name
Mount Desert Island Biological Lab
Department
Type
DUNS #
077470003
City
Salisbury Cove
State
ME
Country
United States
Zip Code
04672
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