Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Core A, the Administrative Core, is responsible for the day-to-day operations of the Molecular Targets Center of Biomedical Research Excellence (MT-COBRE). Core A manages the scientific and administrative aspects of the COBRE. In collaboration with Nancy Roseberry, the COBRE Coordinator, Drs. Miller and Eaton are responsible for oversight of all administrative aspects of the COBRE. This funding has provided an opportunity to recruit five additional faculty to the MT-COBRE, as the original faculty have received new funding and left the COBRE.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR018733-07
Application #
7959803
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2009-07-01
Project End
2010-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
7
Fiscal Year
2009
Total Cost
$181,197
Indirect Cost

  Institution

Name
University of Louisville
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40292

  Publications

Neely, Aaron M; Zhao, Guoping; Schwarzer, Christian et al. (2018) N-(3-Oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts. Cell Microbiol 20:
Schmidt, M Lee; Hobbing, Katharine R; Donninger, Howard et al. (2018) RASSF1A Deficiency Enhances RAS-Driven Lung Tumorigenesis. Cancer Res 78:2614-2623
Garbett, Nichola C; Brock, Guy N; Chaires, Jonathan B et al. (2017) Characterization and classification of lupus patients based on plasma thermograms. PLoS One 12:e0186398
Kendrick, Sarah K; Zheng, Qi; Garbett, Nichola C et al. (2017) Application and interpretation of functional data analysis techniques to differential scanning calorimetry data from lupus patients. PLoS One 12:e0186232
Zhao, Guoping; Neely, Aaron M; Schwarzer, Christian et al. (2016) N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins. Oncotarget 7:5924-42
Garbett, Nichola C; Brock, Guy N (2016) Differential scanning calorimetry as a complementary diagnostic tool for the evaluation of biological samples. Biochim Biophys Acta 1860:981-989
Donninger, Howard; Schmidt, M Lee; Mezzanotte, Jessica et al. (2016) Ras signaling through RASSF proteins. Semin Cell Dev Biol 58:86-95
Lanceta, Lilibeth; Mattingly, Jacob M; Li, Chi et al. (2015) How Heme Oxygenase-1 Prevents Heme-Induced Cell Death. PLoS One 10:e0134144
Schwarzer, Christian; Fu, Zhu; Morita, Takeshi et al. (2015) Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone. J Biol Chem 290:7247-58
Donninger, Howard; Calvisi, Diego F; Barnoud, Thibaut et al. (2015) NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2. J Cell Biol 208:777-89

Showing the most recent 10 out of 148 publications