Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The NCN faculty recruitment component is designed to achieve the critical mass of researchers and technologies for the Center to function as a competitive, productive research enterprise. This will be accomplished by targeted recruitment of key faculty who will bring relevant new research components not currently present at the Center. This is necessary to produce a truly multidisciplinary research enterprise in nanomedicine. These targeted hires bring synergy and expertise in neurooncology, nanomaterials pharmacology, and delivery of imaging agents. These focused hires are essential for the success of the NCN and for making the Center an integrated biomedical research enterprise with a high likelihood of sustained success.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR021937-03
Application #
8167880
Study Section
Special Emphasis Panel (ZRR1-RI-2 (01))
Project Start
2010-07-01
Project End
2011-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
3
Fiscal Year
2010
Total Cost
$300,439
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Other Basic Sciences
Type
Schools of Pharmacy
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Ambardekar, Vishakha V; Wakaskar, Rajesh R; Ye, Zhen et al. (2018) Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration. Int J Pharm 543:130-138
Gaymalov, Zagit; Kabanov, Alexander (2017) RECOPE: How to succeed in bringing ideas from academia to market without compromising ingenuity. Nanomedicine 13:795-800
Karuturi, Bala V K; Tallapaka, Shailendra B; Yeapuri, Pravin et al. (2017) Encapsulation of an EP67-Conjugated CTL Peptide Vaccine in Nanoscale Biodegradable Particles Increases the Efficacy of Respiratory Immunization and Affects the Magnitude and Memory Subsets of Vaccine-Generated Mucosal and Systemic CD8+T Cells in a Diamete Mol Pharm 14:1469-1481
Mahajan, Vivek; Gaymalov, Zagit; Alakhova, Daria et al. (2016) Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers. Data Brief 7:1269-82
Kim, Myung Soo; Haney, Matthew J; Zhao, Yuling et al. (2016) Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells. Nanomedicine 12:655-664
Sharma, Bhawna; Nannuru, Kalyan C; Varney, Michelle L et al. (2015) Host Cxcr2-dependent regulation of mammary tumor growth and metastasis. Clin Exp Metastasis 32:65-72
Zhu, Yu; Li, Jing; Kanvinde, Shrey et al. (2015) Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer. Mol Pharm 12:332-41
Macha, M A; Rachagani, S; Pai, P et al. (2015) MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway. Oncogene 34:1698-708
Haney, Matthew J; Klyachko, Natalia L; Zhao, Yuling et al. (2015) Exosomes as drug delivery vehicles for Parkinson's disease therapy. J Control Release 207:18-30
Karuturi, Bala Vamsi K; Tallapaka, Shailendra B; Phillips, Joy A et al. (2015) Preliminary evidence that the novel host-derived immunostimulant EP67 can act as a mucosal adjuvant. Clin Immunol 161:251-9

Showing the most recent 10 out of 78 publications