Abstract

- Neuroimaging Core The Neuroimaging Core (NC) plays an integral role in the UC Davis ADC (UCD ADC) scientific mission by providing imaging-based biological markers of disease processes in brain structure and function. In vivo imaging of cerebral pathology and brain status provides measures that are central to the overarching scientific theme of the UCD ADC which seeks to use demographic diversity to understand the multiple life course factors that influence brain and cognitive trajectories in old age and transitions to dementia. Building on the success of our previous cycles of funded activities, the NC will continue to provide a comprehensive and expanded set of neuroimaging services ranging from image acquisition and storage to post-processing, creation of standard and customized analytic data sets, and dissemination of imaging data. In addition, the NC will continue to collaborate with other neuroimaging institutions as well as researchers at UC Davis to develop novel state-of- the-art methods for measuring the natural course of late-life brain injury.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG010129-30
Application #
9978585
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
30
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Wang, Tingyan; Qiu, Robin G; Yu, Ming (2018) Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks. Sci Rep 8:9161
Wong, Jonathan M; Gray, John A (2018) Long-Term Depression Is Independent of GluN2 Subunit Composition. J Neurosci 38:4462-4470
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487
Seiler, Stephan; Fletcher, Evan; Hassan-Ali, Kinsy et al. (2018) Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition. Neurobiol Aging 72:14-22
Gavett, Brandon E; Fletcher, Evan; Harvey, Danielle et al. (2018) Ethnoracial differences in brain structure change and cognitive change. Neuropsychology 32:529-540
Crum, Jana; Wilson, Jeffrey; Sabbagh, Marwan (2018) Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia? Alzheimers Res Ther 10:104
Sarnowski, Chloé; Satizabal, Claudia L; DeCarli, Charles et al. (2018) Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology 90:e188-e196
Burke, Shanna L; Cadet, Tamara; Maddux, Marlaina (2018) Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults. J Natl Med Assoc 110:314-325
Gilsanz, Paola; Mayeda, Elizabeth Rose; Glymour, M Maria et al. (2018) Birth in High Infant Mortality States and Dementia Risk in a Cohort of Elderly African American and White Health Care Members. Alzheimer Dis Assoc Disord :
Mungas, Dan; Early, Dawnté R; Glymour, M Maria et al. (2018) Education, bilingualism, and cognitive trajectories: Sacramento Area Latino Aging Study (SALSA). Neuropsychology 32:77-88

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