Abstract

The aims of the core are to continue to develop new models, which includes performing the necessary molecular biology and mouse manipulation (including offering training), and to provide resources and expertise in the construction of targeting vectors, including inducibles, etc. They will also perform cryopreservation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
3P30AG013280-08S1
Application #
6613334
Study Section
Project Start
2002-08-01
Project End
2003-06-30
Budget Start
Budget End
Support Year
8
Fiscal Year
2002
Total Cost
$193,750
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Beaupere, Carine; Dinatto, Leticia; Wasko, Brian M et al. (2018) Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast. Proc Natl Acad Sci U S A 115:9586-9591
Andeen, Nicole K; Yang, Han-Yin; Dai, Dao-Fu et al. (2018) DnaJ Homolog Subfamily B Member 9 Is a Putative Autoantigen in Fibrillary GN. J Am Soc Nephrol 29:231-239
Walters, Ryan O; Arias, Esperanza; Diaz, Antonio et al. (2018) Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans. Cell Rep 25:663-676.e6
Kramer, Philip A; Duan, Jicheng; Gaffrey, Matthew J et al. (2018) Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal muscle. Redox Biol 17:367-376
Kaeberlein, Matt (2018) How healthy is the healthspan concept? Geroscience 40:361-364
Crane, Matthew M; Kaeberlein, Matt (2018) The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells. Curr Opin Syst Biol 8:25-31
Pino, Lindsay K; Searle, Brian C; Bollinger, James G et al. (2017) The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics. Mass Spectrom Rev :
Ting, Ying S; Egertson, Jarrett D; Bollinger, James G et al. (2017) PECAN: library-free peptide detection for data-independent acquisition tandem mass spectrometry data. Nat Methods 14:903-908
Bennett, Christopher F; Kwon, Jane J; Chen, Christine et al. (2017) Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans. PLoS Genet 13:e1006695
Mukherjee, Shubhabrata; Russell, Joshua C; Carr, Daniel T et al. (2017) Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments. Alzheimers Dement 13:1133-1142

Showing the most recent 10 out of 168 publications